C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: myosin, heavy polypeptide 7, cardiac muscle, beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000053093 Myh7 10090 - 14:54970688-54994634 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000102803 Myh7-001 54970688-54994634 protein_coding
  ENSMUST00000149852 Myh7-002 54981174-54987418 retained_intron
  ENSMUST00000153783 Myh7-003 54992692-54994548 protein_coding
  ENSMUST00000168485 Myh7-201 54970767-54994626 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000102803ENSMUST00000149852ENSMUST00000168485
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000102803 0.005±0.00 0.078±0.04 0.086±0.03 0.176±0.10 0.016±0.01 7.692±3.56 0.654±0.68 0.095±0.21 2.680±0.32 124.784±80.34 0.135±0.06 0.047±0.01 N/A
ENSMUST00000149852 N/A N/A N/A N/A 0.019±0.00 N/A N/A N/A N/A N/A 0.042±0.00 0.006±0.00 N/A
ENSMUST00000168485 0.001±0.00 N/A 0.109±0.00 0.007±0.00 0.005±0.00 10.364±1.46 0.344±0.32 0.005±0.00 0.842±0.39 N/A 0.159±0.08 0.011±0.00 0.140±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00090C CIL_00090C_0002 VISTA 14:54638004-55241428
CIL_0009BW CIL_0009BW_0002 VISTA 14:54696106-55297707
CIL_0008Q4 CIL_0008Q4_0002 VISTA 14:54696894-55297224
CIL_0008QH CIL_0008QH_0002 VISTA 14:54703667-55304830
CIL_0004Z7 CIL_0004Z7_0008 CGP 14:54941921-54994634

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000146 IEA microfilament motor activity
GO:0001725 IDA stress fiber
GO:0002026 IEA regulation of the force of heart contraction
GO:0002027 IEA regulation of heart rate
GO:0003779 IEA actin binding
GO:0005516 IEA calmodulin binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005925 IEA focal adhesion
GO:0006200 IEA ATP catabolic process
GO:0006936 IEA muscle contraction
GO:0006941 IEA striated muscle contraction
GO:0007512 IEA adult heart development
GO:0016459 IDA myosin complex
GO:0016887 IEA ATPase activity
GO:0030016 IDA myofibril
GO:0030018 IDA Z disc
GO:0030049 IEA muscle filament sliding
GO:0030898 IEA actin-dependent ATPase activity
GO:0032982 IEA myosin filament
GO:0051015 IEA actin filament binding
GO:0055010 IEA ventricular cardiac muscle tissue morphogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000045242 smyhc3 slow myosin heavy chain 3 protein_coding Danio_rerio
ENSDARG00000071430 smyhc1 slow myosin heavy chain 1 protein_coding Danio_rerio
ENSDARG00000071433 smyhc2 slow myosin heavy chain 2 protein_coding Danio_rerio
ENSDARG00000079564 vmhc ventricular myosin heavy chain protein_coding Danio_rerio
ENSDARG00000079782 vmhcl ventricular myosin heavy chain-like protein_coding Danio_rerio
ENSDARG00000092357 CU633479.5 Uncharacterized protein protein_coding Danio_rerio
ENSDARG00000092902 CR450736.2 Uncharacterized protein protein_coding Danio_rerio
ENSDARG00000093148 CU633479.6 Uncharacterized protein protein_coding Danio_rerio
ENSDARG00000093715 si:ch211-24n20.3 si:ch211-24n20.3 protein_coding Danio_rerio
ENSG00000092054 MYH7 myosin, heavy chain 7, cardiac muscle, beta protein_coding Homo_sapiens

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