C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: myosin IXB
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000099331 MYO9B 9606 + 19:17075781-17214537 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000397274 MYO9B-201 17101656-17213294 protein_coding
  ENST00000593411 MYO9B-006 17102182-17103789 processed_transcript
  ENST00000593533 MYO9B-004 17198118-17206828 retained_intron
  ENST00000594824 MYO9B-002 17075786-17213284 protein_coding
  ENST00000594971 MYO9B-007 17172375-17184898 protein_coding
  ENST00000595618 MYO9B-001 17075781-17213295 protein_coding
  ENST00000595641 MYO9B-003 17101718-17212099 protein_coding
  ENST00000596942 MYO9B-015 17206689-17211744 protein_coding
  ENST00000597073 MYO9B-005 17206774-17213284 protein_coding
  ENST00000597572 MYO9B-017 17210443-17211900 retained_intron
  ENST00000597881 MYO9B-018 17210591-17211940 retained_intron
  ENST00000598101 MYO9B-008 17172813-17184002 retained_intron
  ENST00000598419 MYO9B-016 17207213-17214537 protein_coding
  ENST00000598464 MYO9B-011 17183737-17184955 retained_intron
  ENST00000599420 MYO9B-013 17202129-17206359 retained_intron
  ENST00000601490 MYO9B-012 17184511-17186000 retained_intron
  ENST00000601749 MYO9B-010 17180645-17187939 retained_intron
  ENST00000602158 MYO9B-014 17202870-17206133 nonsense_mediated_decay
  ENST00000602177 MYO9B-009 17172924-17188005 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000397274ENST00000595618ENST00000595641ENST00000597073
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000397274 5.920±0.00 11.392±0.00 2.507±0.00 0.726±0.00 N/A 2.753±0.00 4.053±0.00 N/A N/A 0.840±0.33 4.287±1.05 9.527±0.87 6.928±0.93
ENST00000595618 N/A N/A N/A 1.869±0.00 2.493±0.00 3.391±0.00 N/A 1.980±0.76 7.624±0.00 N/A 3.427±0.00 N/A N/A
ENST00000595641 4.712±0.00 4.925±0.00 1.730±1.37 1.936±0.36 2.387±0.55 N/A 1.294±0.00 1.114±0.00 2.795±1.45 1.256±0.00 4.803±1.06 2.954±0.00 4.979±1.54
ENST00000597073 7.338±0.00 21.345±0.00 5.542±0.00 6.848±0.00 6.165±0.00 N/A 6.220±0.00 2.867±0.00 N/A 3.663±0.00 7.675±1.24 N/A 13.431±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006GM CIL_0006GM_0001 CGP 19:17049729-17214537
CIL_0006GE CIL_0006GE_0001 CGP 19:17075781-17219829

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000146 IDA microfilament motor activity
GO:0001726 IEA ruffle
GO:0002548 IEA monocyte chemotaxis
GO:0003774 IEA motor activity
GO:0003779 IDA actin binding
GO:0005096 IEA GTPase activator activity
GO:0005100 IDA Rho GTPase activator activity
GO:0005515 IPI:IEA protein binding
GO:0005516 IDA calmodulin binding
GO:0005524 IDA:IEA ATP binding
GO:0005622 IEA intracellular
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005884 IEA actin filament
GO:0005938 IDA cell cortex
GO:0006200 IEA ATP catabolic process
GO:0007165 IEA signal transduction
GO:0007264 TAS small GTPase mediated signal transduction
GO:0007266 IC Rho protein signal transduction
GO:0008152 IEA metabolic process
GO:0008270 IEA zinc ion binding
GO:0015629 TAS actin cytoskeleton
GO:0016020 IDA membrane
GO:0016459 IEA myosin complex
GO:0016887 IDA ATPase activity
GO:0030010 IEA establishment of cell polarity
GO:0030027 IEA lamellipodium
GO:0030048 TAS actin filament-based movement
GO:0030898 IEA actin-dependent ATPase activity
GO:0031941 IDA filamentous actin
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0032433 IEA filopodium tip
GO:0035556 IEA intracellular signal transduction
GO:0043008 IEA ATP-dependent protein binding
GO:0043531 IDA ADP binding
GO:0043547 IEA positive regulation of GTPase activity
GO:0046872 IEA metal ion binding
GO:0048246 IEA macrophage chemotaxis
GO:0048471 IDA perinuclear region of cytoplasm
GO:0051015 IEA actin filament binding
GO:0051056 TAS regulation of small GTPase mediated signal transduction
GO:0072673 IEA lamellipodium morphogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074413 MYO9B (1 of 3) myosin IXB protein_coding Danio_rerio
ENSDARG00000077410 myo9b myosin IXb protein_coding Danio_rerio
ENSDARG00000078313 MYO9B (3 of 3) myosin IXB protein_coding Danio_rerio
ENSMUSG00000004677 Myo9b myosin IXb protein_coding Mus_musculus

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