C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein interacting with PRKCA 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000100151 PICK1 9606 + 22:38056311-38075701 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000356976 PICK1-002 38057407-38075701 protein_coding
  ENST00000404072 PICK1-001 38057200-38075701 protein_coding
  ENST00000424694 PICK1-005 38057228-38072608 protein_coding
  ENST00000426258 PICK1-013 38057404-38070891 nonsense_mediated_decay
  ENST00000432756 PICK1-010 38057656-38071728 nonsense_mediated_decay
  ENST00000435166 PICK1-009 38057653-38069085 protein_coding
  ENST00000437453 PICK1-016 38057395-38068114 protein_coding
  ENST00000445628 PICK1-004 38056311-38059306 protein_coding
  ENST00000466374 PICK1-012 38057483-38068085 retained_intron
  ENST00000468288 PICK1-007 38057404-38070891 processed_transcript
  ENST00000469819 PICK1-011 38057407-38065226 retained_intron
  ENST00000472724 PICK1-015 38065113-38072007 retained_intron
  ENST00000476157 PICK1-006 38057404-38058158 retained_intron
  ENST00000484021 PICK1-003 38057255-38075693 retained_intron
  ENST00000494434 PICK1-014 38067477-38072534 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000356976ENST00000404072ENST00000424694ENST00000426258ENST00000437453ENST00000466374ENST00000469819ENST00000472724ENST00000484021ENST00000494434
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000356976 2.253±0.00 3.942±0.00 0.100±0.00 7.999±6.52 5.208±0.00 1.423±0.65 6.278±0.00 9.760±0.00 4.893±0.00 3.785±0.00 7.221±0.00 5.137±2.67 9.818±3.43 10.454±5.71
ENST00000404072 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.662±0.00 N/A
ENST00000424694 N/A N/A N/A N/A N/A N/A N/A N/A 0.748±0.00 N/A N/A N/A N/A N/A
ENST00000426258 N/A N/A N/A N/A 1.210±0.00 N/A N/A N/A N/A N/A N/A 1.277±0.00 N/A N/A
ENST00000437453 N/A N/A N/A N/A N/A N/A N/A N/A 1.628±0.00 N/A N/A 2.004±0.00 N/A N/A
ENST00000466374 N/A N/A 0.596±0.00 N/A N/A N/A N/A N/A N/A 1.124±0.00 N/A 1.120±0.00 N/A N/A
ENST00000469819 N/A N/A 0.578±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000472724 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.864±0.00 N/A N/A N/A N/A
ENST00000484021 N/A N/A N/A 1.352±0.00 N/A N/A 1.081±0.00 0.735±0.66 N/A N/A N/A 5.360±2.24 N/A 4.659±1.41
ENST00000494434 N/A N/A 1.755±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00099H CIL_00099H_0001 VISTA 22:37683926-38284300
CIL_0008KJ CIL_0008KJ_0001 VISTA 22:37685616-38286450
CIL_0008BX CIL_0008BX_0001 VISTA 22:37696030-38296592
CIL_0008KA CIL_0008KA_0001 VISTA 22:37698338-38299192
CIL_00082J CIL_00082J_0001 VISTA 22:37733233-38334508
CIL_0008C1 CIL_0008C1_0001 VISTA 22:37746133-38346872
CIL_00082K CIL_00082K_0001 VISTA 22:37750385-38350990
CIL_0008MM CIL_0008MM_0001 VISTA 22:37872841-38473542
CIL_0003QD CIL_0003QD_0001 CGP 22:37970686-38075701
CIL_0003QE CIL_0003QE_0001 CGP 22:38056311-38084093

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001664 ISS G-protein coupled receptor binding
GO:0002092 ISS positive regulation of receptor internalization
GO:0005080 ISS protein kinase C binding
GO:0005102 ISS receptor binding
GO:0005515 IPI:IEA protein binding
GO:0005737 IDA:IEA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005794 ISS Golgi apparatus
GO:0005886 IDA plasma membrane
GO:0006200 ISS ATP catabolic process
GO:0006468 ISS protein phosphorylation
GO:0006605 IEA protein targeting
GO:0006890 NAS retrograde vesicle-mediated transport, Golgi to ER
GO:0007205 IDA protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0007268 TAS synaptic transmission
GO:0008022 IPI protein C-terminus binding
GO:0015844 IDA monoamine transport
GO:0016887 ISS ATPase activity
GO:0019899 IPI enzyme binding
GO:0019904 IEA:ISS protein domain specific binding
GO:0021782 ISS glial cell development
GO:0030054 IEA cell junction
GO:0030666 TAS endocytic vesicle membrane
GO:0034316 ISS negative regulation of Arp2/3 complex-mediated actin nucleation
GO:0036294 ISS cellular response to decreased oxygen levels
GO:0042149 ISS cellular response to glucose starvation
GO:0042734 IDA presynaptic membrane
GO:0042802 ISS identical protein binding
GO:0043005 ISS neuron projection
GO:0043045 NAS DNA methylation involved in embryo development
GO:0043046 TAS DNA methylation involved in gamete generation
GO:0043113 ISS receptor clustering
GO:0045161 TAS neuronal ion channel clustering
GO:0045202 ISS synapse
GO:0045211 IEA postsynaptic membrane
GO:0046872 IEA metal ion binding
GO:0048471 ISS perinuclear region of cytoplasm
GO:0051015 ISS actin filament binding
GO:0060292 ISS long term synaptic depression
GO:0071933 ISS Arp2/3 complex binding
GO:0097061 ISS dendritic spine organization
GO:0097062 ISS dendritic spine maintenance
GO:0097481 IEA neuronal postsynaptic density

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000071152 pick1 protein interacting with prkca 1 protein_coding Danio_rerio
ENSMUSG00000068206 Pick1 protein interacting with C kinase 1 protein_coding Mus_musculus

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