C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serine palmitoyltransferase, long chain base subunit 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000100596 SPTLC2 9606 - 14:77505997-77616773 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000216484 SPTLC2-001 77505997-77616773 protein_coding
  ENST00000554365 SPTLC2-004 77552120-77557321 retained_intron
  ENST00000554901 SPTLC2-002 77535600-77597321 protein_coding
  ENST00000556264 SPTLC2-006 77552129-77554926 processed_transcript
  ENST00000556607 SPTLC2-005 77512341-77552192 nonsense_mediated_decay
  ENST00000557566 SPTLC2-003 77578766-77597351 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000216484ENST00000554901
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000216484 26.960±0.00 7.777±0.00 3.360±0.00 7.455±1.85 8.203±1.17 7.745±1.08 2.051±0.87 4.632±3.21 2.414±0.82 5.282±0.10 1.780±0.00 4.282±1.31 9.639±0.40 4.757±1.64
ENST00000554901 N/A N/A 4.350±0.00 N/A N/A N/A N/A N/A 3.750±0.00 N/A N/A 2.488±0.38 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00064L CIL_00064L_0002 CGP 14:77474394-77616773
CIL_0004TW CIL_0004TW_0001 CGP 14:77505997-77708020

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004758 IDA serine C-palmitoyltransferase activity
GO:0005739 IEA mitochondrion
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006665 TAS sphingolipid metabolic process
GO:0006686 IEA sphingomyelin biosynthetic process
GO:0009058 IEA biosynthetic process
GO:0016021 IEA integral component of membrane
GO:0017059 IDA serine C-palmitoyltransferase complex
GO:0030148 TAS sphingolipid biosynthetic process
GO:0030170 IEA pyridoxal phosphate binding
GO:0044281 TAS small molecule metabolic process
GO:0046511 IEA sphinganine biosynthetic process
GO:0046512 IEA sphingosine biosynthetic process
GO:0046513 IEA ceramide biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018976 sptlc2a serine palmitoyltransferase, long chain base subunit 2a protein_coding Danio_rerio
ENSDARG00000074287 sptlc2b serine palmitoyltransferase, long chain base subunit 2b protein_coding Danio_rerio
ENSMUSG00000021036 Sptlc2 serine palmitoyltransferase, long chain base subunit 2 protein_coding Mus_musculus

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