C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SIX homeobox 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000100625 SIX4 9606 - 14:60709528-60724348 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000216513 SIX4-001 60709528-60724134 protein_coding
  ENST00000554079 SIX4-002 60713167-60723165 processed_transcript
  ENST00000556952 SIX4-004 60719802-60724348 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000216513ENST00000554079ENST00000556952
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000216513 0.252±0.00 0.072±0.00 0.073±0.00 0.185±0.00 0.441±0.00 0.166±0.00 0.016±0.00 0.588±0.00 N/A 0.696±0.00 3.191±0.00 0.589±0.36 0.297±0.08 0.443±0.00
ENST00000554079 N/A N/A N/A 0.120±0.00 1.041±0.00 N/A N/A N/A 0.101±0.00 N/A 0.789±0.00 N/A N/A N/A
ENST00000556952 N/A N/A N/A N/A N/A N/A 0.032±0.00 N/A N/A N/A N/A N/A 0.314±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008MW CIL_0008MW_0001 VISTA 14:60353481-60955733
CIL_0006SM CIL_0006SM_0002 CGP 14:60643415-60724348
CIL_0006SL CIL_0006SL_0002 CGP 14:60709528-60969953

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007519 IEA skeletal muscle tissue development
GO:0008582 IEA regulation of synaptic growth at neuromuscular junction
GO:0008584 IEA male gonad development
GO:0009653 TAS anatomical structure morphogenesis
GO:0010468 IEA regulation of gene expression
GO:0030238 IEA male sex determination
GO:0030910 IEA olfactory placode formation
GO:0032880 IEA regulation of protein localization
GO:0042472 IEA inner ear morphogenesis
GO:0043524 IEA negative regulation of neuron apoptotic process
GO:0043565 IEA sequence-specific DNA binding
GO:0043586 IEA tongue development
GO:0045214 IEA sarcomere organization
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046661 IEA male sex differentiation
GO:0048538 IEA thymus development
GO:0048699 IEA generation of neurons
GO:0048701 IEA embryonic cranial skeleton morphogenesis
GO:0048704 IEA embryonic skeletal system morphogenesis
GO:0048856 IEA anatomical structure development
GO:0050678 IEA regulation of epithelial cell proliferation
GO:0051451 IEA myoblast migration
GO:0060037 IEA pharyngeal system development
GO:0061055 IEA myotome development
GO:0061197 IEA fungiform papilla morphogenesis
GO:0061551 IEA trigeminal ganglion development
GO:0072075 IEA metanephric mesenchyme development
GO:0072095 IEA regulation of branch elongation involved in ureteric bud branching
GO:0072107 IEA positive regulation of ureteric bud formation
GO:0090190 IEA positive regulation of branching involved in ureteric bud morphogenesis
GO:0098528 IEA skeletal muscle fiber differentiation
GO:1902725 IEA negative regulation of satellite cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004695 six4a sine oculis homeobox homolog 4a protein_coding Danio_rerio
ENSDARG00000031983 six4b sine oculis homeobox homolog 4b protein_coding Danio_rerio
ENSMUSG00000034460 Six4 sine oculis-related homeobox 4 protein_coding Mus_musculus

Loading