C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: signal recognition particle 54kDa
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000100883 SRP54 9606 + 14:34981957-35029567 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000216774 SRP54-201 34982898-35029565 protein_coding
  ENST00000546080 SRP54-202 34982898-35029565 protein_coding
  ENST00000553544 SRP54-009 34982973-34996924 retained_intron
  ENST00000553923 SRP54-012 35014758-35019391 retained_intron
  ENST00000554803 SRP54-005 34982682-34999610 protein_coding
  ENST00000555317 SRP54-008 34982992-34999866 retained_intron
  ENST00000555535 SRP54-007 34993244-35004608 processed_transcript
  ENST00000555557 SRP54-002 34983025-35029454 protein_coding
  ENST00000555746 SRP54-006 34982701-35000987 protein_coding
  ENST00000556380 SRP54-010 34983105-35013434 nonsense_mediated_decay
  ENST00000556445 SRP54-011 35018629-35019358 retained_intron
  ENST00000556992 SRP54-013 35027730-35029135 retained_intron
  ENST00000556994 SRP54-001 34981957-35029567 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000216774ENST00000555557ENST00000556994
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000216774 4.793±0.00 N/A 3.076±0.00 6.613±0.86 3.654±0.09 4.907±0.64 2.434±0.45 9.055±2.83 3.874±0.57 3.987±2.29 1.985±0.75 15.164±5.04 9.441±4.00 17.437±6.12
ENST00000555557 8.531±0.00 8.768±0.00 N/A 8.060±5.36 7.542±0.00 4.099±0.00 2.947±2.28 10.035±0.00 4.544±2.75 4.483±0.00 5.369±0.00 12.591±12.96 4.570±0.70 24.698±8.89
ENST00000556994 N/A 3.218±0.00 N/A N/A N/A N/A 2.044±0.00 N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00045L CIL_00045L_0001 CGP 14:34981957-35113130

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003924 IEA:IDA GTPase activity
GO:0005525 IEA:IDA GTP binding
GO:0005634 IDA nucleus
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0005786 IDA signal recognition particle, endoplasmic reticulum targeting
GO:0005829 TAS cytosol
GO:0006184 IEA GTP catabolic process
GO:0006412 TAS translation
GO:0006614 IEA:IC SRP-dependent cotranslational protein targeting to membrane
GO:0006616 ISS SRP-dependent cotranslational protein targeting to membrane, translocation
GO:0006617 ISS SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition
GO:0008144 IDA drug binding
GO:0008312 IEA:IDA 7S RNA binding
GO:0010467 TAS gene expression
GO:0019003 IDA GDP binding
GO:0030942 IDA endoplasmic reticulum signal peptide binding
GO:0042493 IDA response to drug
GO:0043021 IDA ribonucleoprotein complex binding
GO:0044267 TAS cellular protein metabolic process
GO:0044822 IDA poly(A) RNA binding
GO:0045047 IMP protein targeting to ER
GO:0048500 IEA signal recognition particle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003813 srp54 signal recognition particle 54 protein_coding Danio_rerio
ENSMUSG00000073079 Srp54a signal recognition particle 54A protein_coding Mus_musculus
ENSMUSG00000079108 Srp54b signal recognition particle 54B protein_coding Mus_musculus

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