C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: N-myc downstream regulated 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000104419 NDRG1 9606 - 8:133237171-133302022 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000323851 NDRG1-002 133237171-133297237 protein_coding
  ENST00000414097 NDRG1-001 133237176-133297586 protein_coding
  ENST00000517331 NDRG1-023 133244380-133259446 processed_transcript
  ENST00000517599 NDRG1-005 133237176-133297252 nonsense_mediated_decay
  ENST00000517745 NDRG1-024 133258996-133264581 retained_intron
  ENST00000518010 NDRG1-025 133256809-133297252 processed_transcript
  ENST00000518066 NDRG1-030 133238767-133297252 protein_coding
  ENST00000518094 NDRG1-022 133259095-133262257 retained_intron
  ENST00000518176 NDRG1-003 133238538-133297237 protein_coding
  ENST00000518480 NDRG1-017 133256816-133297256 protein_coding
  ENST00000519228 NDRG1-012 133256819-133297958 protein_coding
  ENST00000519278 NDRG1-006 133237176-133256228 retained_intron
  ENST00000519580 NDRG1-014 133256840-133296555 protein_coding
  ENST00000520230 NDRG1-010 133256785-133302022 protein_coding
  ENST00000520943 NDRG1-011 133258379-133298458 protein_coding
  ENST00000521026 NDRG1-008 133237176-133244503 retained_intron
  ENST00000521414 NDRG1-007 133237176-133249488 processed_transcript
  ENST00000521438 NDRG1-009 133237176-133241527 retained_intron
  ENST00000521544 NDRG1-016 133258416-133297252 protein_coding
  ENST00000521664 NDRG1-027 133246627-133254882 retained_intron
  ENST00000522377 NDRG1-026 133246623-133297239 nonsense_mediated_decay
  ENST00000522476 NDRG1-004 133238698-133297252 protein_coding
  ENST00000522665 NDRG1-029 133241878-133250460 retained_intron
  ENST00000522738 NDRG1-015 133259218-133296536 protein_coding
  ENST00000522890 NDRG1-013 133256840-133297092 protein_coding
  ENST00000523642 NDRG1-028 133241874-133244660 retained_intron
  ENST00000523892 NDRG1-020 133262047-133297256 protein_coding
  ENST00000523931 NDRG1-021 133262060-133264992 retained_intron
  ENST00000537882 NDRG1-201 133237171-133297304 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000323851ENST00000518176ENST00000519278ENST00000521026ENST00000521438
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000323851 72.334±0.00 33.866±0.00 9.158±0.00 169.357±0.00 37.191±29.16 69.977±61.89 20.872±0.00 67.221±66.73 8.418±0.67 93.174±80.00 20.145±0.00 73.670±39.05 91.075±38.24 27.563±12.02
ENST00000518176 N/A N/A N/A N/A N/A N/A N/A 5.909±0.00 N/A N/A N/A N/A N/A N/A
ENST00000519278 9.657±0.00 N/A 10.275±0.00 N/A N/A 3.767±0.00 0.674±0.00 N/A 7.662±0.00 8.596±0.00 2.038±0.00 5.910±0.00 N/A N/A
ENST00000521026 27.015±0.00 31.990±0.00 N/A 14.807±0.00 N/A 77.753±0.00 N/A 20.686±19.75 N/A N/A N/A 33.469±21.03 14.268±0.00 21.227±8.65
ENST00000521438 N/A N/A N/A N/A N/A N/A N/A 0.816±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009D4 CIL_0009D4_0001 VISTA 8:132792656-133394938
CIL_0006FT CIL_0006FT_0002 CGP 8:133191039-133302022
CIL_00094T CIL_00094T_0001 VISTA 8:133226403-133828417
CIL_0004PW CIL_0004PW_0001 CGP 8:133237171-133571940

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005813 IDA centrosome
GO:0005874 IDA microtubule
GO:0005886 IDA plasma membrane
GO:0005913 IDA cell-cell adherens junction
GO:0008017 IDA microtubule binding
GO:0008219 IEA cell death
GO:0010038 TAS response to metal ion
GO:0015630 IDA microtubule cytoskeleton
GO:0017137 IDA Rab GTPase binding
GO:0030330 IEP DNA damage response, signal transduction by p53 class mediator
GO:0032287 IEA peripheral nervous system myelin maintenance
GO:0043015 IDA gamma-tubulin binding
GO:0045296 IDA cadherin binding
GO:0045576 IEA mast cell activation
GO:0048471 IDA perinuclear region of cytoplasm
GO:0055038 IDA recycling endosome membrane
GO:0070062 IDA extracellular vesicular exosome
GO:0071456 IEP cellular response to hypoxia
GO:0090232 IDA positive regulation of spindle checkpoint

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010420 ndrg1b N-myc downstream regulated gene 1b protein_coding Danio_rerio
ENSDARG00000032849 ndrg1a N-myc downstream regulated gene 1a protein_coding Danio_rerio
ENSMUSG00000005125 Ndrg1 N-myc downstream regulated gene 1 protein_coding Mus_musculus

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