C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: troponin T type 1 (skeletal, slow)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000105048 TNNT1 9606 - 19:55132794-55149354 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000291901 TNNT1-003 55132794-55149206 protein_coding
  ENST00000356783 TNNT1-001 55132794-55149206 protein_coding
  ENST00000536926 TNNT1-201 55132832-55149206 protein_coding
  ENST00000585321 TNNT1-011 55132865-55146942 protein_coding
  ENST00000586282 TNNT1-006 55145400-55149206 retained_intron
  ENST00000586649 TNNT1-018 55132950-55137177 protein_coding
  ENST00000587089 TNNT1-014 55132876-55146454 nonsense_mediated_decay
  ENST00000587465 TNNT1-012 55132835-55146949 protein_coding
  ENST00000587758 TNNT1-005 55132794-55149193 protein_coding
  ENST00000588147 TNNT1-004 55138018-55149206 protein_coding
  ENST00000588426 TNNT1-007 55132794-55149206 protein_coding
  ENST00000588981 TNNT1-002 55132794-55149354 protein_coding
  ENST00000589226 TNNT1-010 55137976-55147308 protein_coding
  ENST00000589745 TNNT1-016 55132828-55140922 protein_coding
  ENST00000592920 TNNT1-008 55138005-55149206 processed_transcript
  ENST00000593046 TNNT1-009 55137103-55147346 protein_coding
  ENST00000593194 TNNT1-015 55132826-55141891 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000291901ENST00000356783ENST00000585321ENST00000586649ENST00000587089ENST00000587465ENST00000587758ENST00000588147ENST00000589226ENST00000589745ENST00000592920ENST00000593046ENST00000593194
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000291901 N/A N/A N/A N/A 35.379±34.06 N/A 0.758±0.00 N/A 0.495±0.00 N/A 761.522±110.24 0.659±0.00 N/A 47.249±0.00
ENST00000356783 N/A N/A 0.154±0.00 N/A 31.420±0.00 0.471±0.00 N/A N/A N/A N/A 519.551±0.00 N/A N/A 49.350±0.00
ENST00000585321 0.114±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.968±0.00 2.700±0.00 N/A
ENST00000586649 0.375±0.00 N/A 0.538±0.00 N/A N/A N/A N/A 0.216±0.00 N/A N/A N/A N/A N/A N/A
ENST00000587089 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 6.019±0.00
ENST00000587465 N/A 0.131±0.00 N/A N/A N/A 0.339±0.00 N/A N/A N/A N/A N/A 3.855±3.65 3.646±0.00 N/A
ENST00000587758 0.157±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000588147 N/A N/A N/A N/A N/A 0.097±0.00 N/A 0.249±0.12 N/A N/A N/A N/A 15.290±0.00 6.466±0.00
ENST00000589226 0.174±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.730±0.00 N/A N/A
ENST00000589745 N/A 0.697±0.00 N/A 7.946±5.16 N/A 0.381±0.00 N/A N/A 2.477±2.32 0.685±0.00 977.775±0.00 1.748±0.00 N/A N/A
ENST00000592920 N/A 0.303±0.00 N/A N/A N/A N/A N/A N/A N/A 0.472±0.00 N/A N/A N/A N/A
ENST00000593046 N/A N/A N/A N/A 0.829±0.00 0.256±0.00 0.334±0.00 N/A 0.653±0.00 N/A N/A 0.621±0.00 7.122±0.00 N/A
ENST00000593194 N/A N/A N/A 1.656±0.00 93.775±0.00 0.344±0.00 N/A N/A N/A N/A 729.438±0.00 1.771±0.00 9.752±10.27 63.187±60.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003RJ CIL_0003RJ_0001 CGP 19:55090913-55149354
CIL_00065K CIL_00065K_0001 CGP 19:55132794-55157773

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003009 IMP skeletal muscle contraction
GO:0005523 IMP tropomyosin binding
GO:0005829 TAS cytosol
GO:0005861 IEA:IMP troponin complex
GO:0006937 IEA regulation of muscle contraction
GO:0030049 TAS muscle filament sliding
GO:0031014 IEA troponin T binding
GO:0031444 IEA slow-twitch skeletal muscle fiber contraction
GO:0045932 IDA negative regulation of muscle contraction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000037954 tnnt1 troponin T type 1 (skeletal, slow) protein_coding Danio_rerio
ENSMUSG00000064179 Tnnt1 troponin T1, skeletal, slow protein_coding Mus_musculus

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