C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ATPase, Na+/K+ transporting, alpha 3 polypeptide
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000105409 ATP1A3 9606 - 19:41966582-41997497 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000302102 ATP1A3-001 41966582-41994276 protein_coding
  ENST00000441343 ATP1A3-002 41966582-41994214 non_stop_decay
  ENST00000465007 ATP1A3-009 41988205-41988557 retained_intron
  ENST00000468774 ATP1A3-006 41987999-41993522 processed_transcript
  ENST00000473086 ATP1A3-011 41985067-41997497 protein_coding
  ENST00000485672 ATP1A3-003 41984254-41985342 retained_intron
  ENST00000543770 ATP1A3-007 41966621-41993467 protein_coding
  ENST00000545399 ATP1A3-008 41966584-41994260 protein_coding
  ENST00000602133 ATP1A3-005 41966584-41994079 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000302102ENST00000441343ENST00000468774ENST00000473086ENST00000485672ENST00000543770ENST00000545399ENST00000602133
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000302102 0.069±0.00 N/A 102.173±65.79 N/A 4.709±0.00 56.247±46.28 N/A 0.284±0.00 N/A N/A N/A 0.049±0.00 17.675±4.11
ENST00000441343 N/A 0.598±0.00 N/A N/A N/A N/A N/A N/A 0.207±0.00 N/A 0.227±0.12 0.113±0.06 34.882±22.84
ENST00000468774 N/A N/A N/A N/A N/A N/A N/A 0.035±0.00 N/A N/A N/A N/A N/A
ENST00000473086 N/A N/A N/A N/A N/A N/A N/A 0.105±0.00 N/A N/A 0.126±0.00 N/A N/A
ENST00000485672 N/A N/A N/A 0.291±0.00 N/A N/A 0.114±0.00 0.022±0.00 0.138±0.00 0.235±0.00 0.113±0.00 N/A N/A
ENST00000543770 N/A 0.525±0.00 N/A N/A N/A N/A 0.007±0.00 0.016±0.00 N/A 0.128±0.13 0.093±0.06 0.555±0.00 N/A
ENST00000545399 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 15.779±0.00
ENST00000602133 N/A N/A 12.172±0.00 0.092±0.02 N/A N/A 0.019±0.00 N/A 0.095±0.00 0.019±0.00 0.029±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00030U CIL_00030U_0001 CGP 19:41956681-41997497
CIL_0003YN CIL_0003YN_0001 CGP 19:41966582-42069498

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0005391 IDA:IEA sodium:potassium-exchanging ATPase activity
GO:0005515 IEA protein binding
GO:0005524 IEA:NAS ATP binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005783 IDA endoplasmic reticulum
GO:0005794 IDA Golgi apparatus
GO:0005886 IDA plasma membrane
GO:0005890 IDA sodium:potassium-exchanging ATPase complex
GO:0006754 IEA ATP biosynthetic process
GO:0006813 IEA potassium ion transport
GO:0006814 IEA sodium ion transport
GO:0006883 IDA cellular sodium ion homeostasis
GO:0007613 IEA memory
GO:0008344 IEA adult locomotory behavior
GO:0008542 IEA visual learning
GO:0010107 IDA potassium ion import
GO:0015077 IEA monovalent inorganic cation transmembrane transporter activity
GO:0016021 NAS:IEA integral component of membrane
GO:0019829 IEA cation-transporting ATPase activity
GO:0030007 IDA cellular potassium ion homeostasis
GO:0030424 IEA axon
GO:0031748 IEA D1 dopamine receptor binding
GO:0031982 IDA vesicle
GO:0034220 TAS ion transmembrane transport
GO:0035235 IEA ionotropic glutamate receptor signaling pathway
GO:0036376 IDA sodium ion export from cell
GO:0042493 IEA response to drug
GO:0043209 IEA myelin sheath
GO:0044326 IEA dendritic spine neck
GO:0044327 IEA dendritic spine head
GO:0045202 ISS synapse
GO:0046872 IEA metal ion binding
GO:0051087 IPI chaperone binding
GO:0055085 TAS transmembrane transport
GO:0071383 NAS cellular response to steroid hormone stimulus
GO:0086064 TAS cell communication by electrical coupling involved in cardiac conduction
GO:0098655 IEA cation transmembrane transport
GO:1903416 NAS response to glycoside
GO:1990239 NAS steroid hormone binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018259 atp1a3a ATPase, Na+/K+ transporting, alpha 3a polypeptide protein_coding Danio_rerio
ENSDARG00000036815 atp1a3b ATPase, Na+/K+ transporting, alpha 3b polypeptide protein_coding Danio_rerio
ENSMUSG00000040907 Atp1a3 ATPase, Na+/K+ transporting, alpha 3 polypeptide protein_coding Mus_musculus

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