C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: TCF3 (E2A) fusion partner (in childhood Leukemia)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000105619 TFPT 9606 - 19:54107013-54115675 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000391757 TFPT-005 54107020-54115288 protein_coding
  ENST00000391758 TFPT-002 54107020-54115074 protein_coding
  ENST00000391759 TFPT-003 54107013-54115675 protein_coding
  ENST00000420715 TFPT-006 54107020-54115285 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainKidneyOvaryPlacentaTestisENST00000391759
Transcript ID Brain Kidney Ovary Placenta Testis
ENST00000391759 4.746±0.00 2.286±0.00 5.961±3.83 22.756±0.00 9.445±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00021A CIL_00021A_0001 CGP 19:54094668-54109257
CIL_0005NN CIL_0005NN_0001 CGP 19:54102728-54115675
CIL_0005O3 CIL_0005O3_0001 CGP 19:54107013-54131719

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 ISS DNA binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005730 IDA nucleolus
GO:0005737 ISS cytoplasm
GO:0005884 IEA actin filament
GO:0006281 IEA DNA repair
GO:0006310 IEA DNA recombination
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006915 IEA apoptotic process
GO:0019901 IEA protein kinase binding
GO:0031011 IDA Ino80 complex
GO:0043065 IEA positive regulation of apoptotic process
GO:0046982 IEA protein heterodimerization activity
GO:0097190 IDA apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000089572 TFPT TCF3 fusion partner homolog (tfpt), mRNA protein_coding Danio_rerio
ENSMUSG00000006335 Tfpt TCF3 (E2A) fusion partner protein_coding Mus_musculus

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