C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cancer susceptibility candidate 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000108349 CASC3 9606 + 17:40140318-40172183 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000264645 CASC3-001 40140323-40172183 protein_coding
  ENST00000394114 CASC3-005 40168438-40172164 retained_intron
  ENST00000418132 CASC3-004 40140318-40167080 retained_intron
  ENST00000474190 CASC3-002 40161797-40166857 nonsense_mediated_decay
  ENST00000577605 CASC3-008 40163912-40168255 nonsense_mediated_decay
  ENST00000579238 CASC3-011 40167366-40168119 retained_intron
  ENST00000581849 CASC3-009 40140537-40162023 retained_intron
  ENST00000583649 CASC3-006 40140544-40141547 retained_intron
  ENST00000583902 CASC3-010 40167917-40169379 retained_intron
  ENST00000584997 CASC3-007 40140842-40161864 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000264645ENST00000418132ENST00000474190
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000264645 38.735±0.00 22.297±0.00 1.326±0.00 16.341±10.59 15.681±9.44 13.046±7.58 7.315±5.53 12.977±9.20 7.862±2.34 14.865±9.97 12.724±8.46 30.736±18.05 15.530±2.59 48.362±8.32
ENST00000418132 N/A N/A 6.138±0.00 1.549±0.00 2.245±0.00 4.135±0.00 1.591±0.00 N/A 8.466±0.00 3.876±0.00 N/A 3.705±0.00 N/A N/A
ENST00000474190 N/A N/A N/A 3.726±0.00 N/A N/A N/A 2.571±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00098Y CIL_00098Y_0001 VISTA 17:39768583-40372873
CIL_0007GO CIL_0007GO_0001 CGP 17:40122298-40172183
CIL_0002GI CIL_0002GI_0001 CGP 17:40140318-40195656

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000184 TAS nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005829 TAS cytosol
GO:0006397 IEA mRNA processing
GO:0006417 IEA regulation of translation
GO:0006950 IEA response to stress
GO:0008150 ND biological_process
GO:0008298 IEA intracellular mRNA localization
GO:0008380 IEA RNA splicing
GO:0010467 TAS gene expression
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0019899 IPI enzyme binding
GO:0030529 IEA ribonucleoprotein complex
GO:0031625 IPI ubiquitin protein ligase binding
GO:0035145 IDA exon-exon junction complex
GO:0042802 IDA identical protein binding
GO:0044822 IDA poly(A) RNA binding
GO:0051028 IEA mRNA transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000029911 casc3 cancer susceptibility candidate 3 protein_coding Danio_rerio
ENSMUSG00000078676 Casc3 cancer susceptibility candidate 3 protein_coding Mus_musculus

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