C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Rap guanine nucleotide exchange factor (GEF)-like 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000108352 RAPGEFL1 9606 + 17:40177010-40195656 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000264644 RAPGEFL1-007 40177095-40195656 protein_coding
  ENST00000456989 RAPGEFL1-005 40177010-40193788 protein_coding
  ENST00000469209 RAPGEFL1-003 40189210-40191037 retained_intron
  ENST00000496032 RAPGEFL1-002 40191470-40192966 retained_intron
  ENST00000538884 RAPGEFL1-006 40177115-40184294 protein_coding
  ENST00000538981 RAPGEFL1-008 40181239-40188954 protein_coding
  ENST00000541245 RAPGEFL1-012 40178249-40184308 protein_coding
  ENST00000543876 RAPGEFL1-011 40177055-40189326 protein_coding
  ENST00000544503 RAPGEFL1-004 40177077-40194190 protein_coding
  ENST00000545893 RAPGEFL1-010 40188538-40193831 retained_intron
  ENST00000613811 RAPGEFL1-001 40177495-40191357 protein_coding
  ENST00000620260 RAPGEFL1-201 40177862-40195654 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000264644ENST00000456989ENST00000469209ENST00000496032ENST00000541245ENST00000543876ENST00000544503ENST00000545893ENST00000613811ENST00000620260
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000264644 N/A N/A N/A N/A N/A N/A 0.064±0.01 N/A N/A N/A N/A 1.945±1.36 0.138±0.03 N/A
ENST00000456989 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.096±0.00
ENST00000469209 N/A N/A N/A N/A 1.572±0.00 N/A N/A N/A N/A N/A 0.409±0.00 N/A N/A N/A
ENST00000496032 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.910±0.00 N/A N/A
ENST00000541245 N/A N/A N/A N/A N/A N/A N/A 1.503±0.00 N/A N/A N/A N/A 0.540±0.00 N/A
ENST00000543876 N/A N/A 0.474±0.00 N/A N/A N/A 0.196±0.00 2.015±0.00 N/A N/A N/A N/A 0.219±0.00 N/A
ENST00000544503 N/A N/A N/A N/A N/A N/A 0.150±0.00 N/A N/A 0.298±0.00 N/A 0.186±0.00 0.127±0.00 N/A
ENST00000545893 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.529±0.00 N/A N/A N/A N/A
ENST00000613811 N/A N/A N/A 1.635±0.00 0.492±0.00 N/A N/A N/A 0.677±0.00 N/A N/A N/A 0.136±0.00 N/A
ENST00000620260 0.266±0.00 0.268±0.00 N/A 9.150±0.00 0.767±0.00 2.612±1.84 0.072±0.00 0.307±0.00 N/A 0.994±0.00 N/A 2.124±2.16 N/A 1.527±0.78

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00098Y CIL_00098Y_0001 VISTA 17:39768583-40372873
CIL_0002GI CIL_0002GI_0001 CGP 17:40140318-40195656
CIL_0002GJ CIL_0002GJ_0001 CGP 17:40177010-40284136

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005057 IEA receptor signaling protein activity
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0007165 IEA signal transduction
GO:0007186 TAS G-protein coupled receptor signaling pathway
GO:0007264 IEA small GTPase mediated signal transduction
GO:0007399 TAS nervous system development
GO:0016020 TAS membrane
GO:0035556 IEA intracellular signal transduction
GO:0043547 IEA positive regulation of GTPase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000079912 RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1 protein_coding Danio_rerio
ENSMUSG00000038020 Rapgefl1 Rap guanine nucleotide exchange factor (GEF)-like 1 protein_coding Mus_musculus

Loading