C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: RAD51 paralog C
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000108384 RAD51C 9606 + 17:58692573-58735611 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000337432 RAD51C-001 58692573-58735611 protein_coding
  ENST00000413590 RAD51C-011 58695148-58734229 protein_coding
  ENST00000421782 RAD51C-013 58692628-58695336 protein_coding
  ENST00000425173 RAD51C-006 58694990-58709876 protein_coding
  ENST00000461271 RAD51C-008 58692573-58709911 protein_coding
  ENST00000461706 RAD51C-012 58732332-58734331 retained_intron
  ENST00000475762 RAD51C-002 58692602-58734331 nonsense_mediated_decay
  ENST00000476741 RAD51C-005 58692602-58694880 processed_transcript
  ENST00000482007 RAD51C-003 58692615-58734327 nonsense_mediated_decay
  ENST00000486827 RAD51C-004 58692606-58695333 nonsense_mediated_decay
  ENST00000487525 RAD51C-007 58692606-58734325 nonsense_mediated_decay
  ENST00000487921 RAD51C-009 58692576-58705913 processed_transcript
  ENST00000578151 RAD51C-017 58709819-58734342 retained_intron
  ENST00000581221 RAD51C-015 58709639-58734327 retained_intron
  ENST00000583539 RAD51C-018 58692573-58732766 protein_coding
  ENST00000584617 RAD51C-014 58692663-58732519 nonsense_mediated_decay
  ENST00000584804 RAD51C-016 58709859-58734331 protein_coding
  ENST00000622327 RAD51C-019 58695050-58700253 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000337432ENST00000413590ENST00000421782ENST00000425173ENST00000461271ENST00000475762ENST00000482007ENST00000486827ENST00000487525ENST00000487921ENST00000581221ENST00000583539ENST00000584617ENST00000584804ENST00000622327
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000337432 N/A N/A N/A 0.903±0.08 0.667±0.00 0.324±0.00 0.859±0.00 0.734±0.00 0.280±0.00 0.471±0.00 0.387±0.00 0.887±0.00 0.772±0.00 N/A
ENST00000413590 N/A N/A N/A 3.015±0.08 1.449±0.44 N/A 2.437±1.46 N/A N/A N/A N/A 3.233±0.98 5.659±0.00 7.542±1.91
ENST00000421782 2.163±0.00 7.723±0.00 N/A N/A N/A N/A N/A 3.154±0.00 N/A 1.939±0.00 N/A N/A 4.666±0.00 N/A
ENST00000425173 N/A N/A N/A N/A 0.492±0.00 N/A N/A 0.656±0.00 N/A 1.609±0.00 N/A N/A N/A N/A
ENST00000461271 N/A N/A 0.486±0.00 2.574±0.15 N/A 3.050±0.00 N/A N/A 1.643±0.02 N/A N/A 3.134±1.13 N/A 5.059±0.00
ENST00000475762 N/A 1.222±0.00 N/A 0.991±0.04 N/A 0.688±0.00 N/A N/A N/A 0.592±0.08 N/A N/A 1.105±0.00 N/A
ENST00000482007 1.113±0.00 N/A N/A 2.921±0.00 2.204±0.00 3.339±0.00 3.267±0.00 3.430±0.00 1.359±0.00 1.070±0.00 1.244±0.00 4.670±1.85 3.896±1.17 7.477±4.05
ENST00000486827 N/A N/A N/A 1.183±0.00 N/A N/A N/A N/A N/A N/A N/A 0.846±0.00 N/A N/A
ENST00000487525 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.304±0.00 3.501±1.03
ENST00000487921 N/A N/A N/A N/A N/A 1.149±0.00 0.812±0.00 N/A N/A N/A 2.118±0.00 N/A N/A N/A
ENST00000581221 N/A N/A N/A 4.069±0.00 0.807±0.00 N/A 1.576±0.00 2.242±0.00 N/A N/A 1.990±0.00 N/A N/A N/A
ENST00000583539 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.737±0.00 N/A N/A
ENST00000584617 2.148±0.00 N/A N/A N/A N/A N/A N/A 2.882±0.00 N/A N/A N/A N/A N/A N/A
ENST00000584804 N/A N/A N/A N/A N/A 2.770±0.00 N/A N/A N/A N/A 2.710±0.00 N/A N/A N/A
ENST00000622327 N/A N/A N/A N/A N/A 1.243±0.00 1.269±0.00 N/A N/A 1.688±0.00 2.349±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000566 CIL_000566_0002 CGP 17:58692573-58985176

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0000400 IDA four-way junction DNA binding
GO:0000724 IMP double-strand break repair via homologous recombination
GO:0000737 IEA DNA catabolic process, endonucleolytic
GO:0003677 IEA:TAS DNA binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005657 IDA replication fork
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0006200 IEA ATP catabolic process
GO:0006259 IEA DNA metabolic process
GO:0006281 IDA DNA repair
GO:0006310 IDA DNA recombination
GO:0007062 ISS sister chromatid cohesion
GO:0007066 IEA female meiosis sister chromatid cohesion
GO:0007131 IEA reciprocal meiotic recombination
GO:0007141 IEA male meiosis I
GO:0007283 IEA spermatogenesis
GO:0007596 TAS blood coagulation
GO:0008094 IEA DNA-dependent ATPase activity
GO:0008821 IMP crossover junction endodeoxyribonuclease activity
GO:0010971 IMP positive regulation of G2/M transition of mitotic cell cycle
GO:0033063 IDA Rad51B-Rad51C-Rad51D-XRCC2 complex
GO:0033065 IDA Rad51C-XRCC3 complex
GO:0048471 IDA perinuclear region of cytoplasm
GO:0048476 IDA Holliday junction resolvase complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000068919 rad51c rad51 homolog C (S. cerevisiae) protein_coding Danio_rerio
ENSMUSG00000007646 Rad51c RAD51 homolog C protein_coding Mus_musculus

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