C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tripartite motif containing 37
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000108395 TRIM37 9606 - 17:58982638-59106921 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000262294 TRIM37-002 58998202-59106721 protein_coding
  ENST00000393065 TRIM37-003 58998987-59106826 protein_coding
  ENST00000393066 TRIM37-001 58982651-59106921 protein_coding
  ENST00000577554 TRIM37-004 58998200-59106740 nonsense_mediated_decay
  ENST00000580122 TRIM37-010 59079798-59106459 nonsense_mediated_decay
  ENST00000580620 TRIM37-006 59087979-59106664 retained_intron
  ENST00000580973 TRIM37-007 59075684-59106715 nonsense_mediated_decay
  ENST00000581468 TRIM37-008 59061089-59081162 protein_coding
  ENST00000582852 TRIM37-009 59064152-59079807 retained_intron
  ENST00000583387 TRIM37-005 59087980-59106711 retained_intron
  ENST00000583945 TRIM37-011 58982651-59012407 protein_coding
  ENST00000584889 TRIM37-013 59088226-59106468 protein_coding
  ENST00000585287 TRIM37-012 58982638-59015617 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000262294ENST00000393065ENST00000393066ENST00000577554
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000262294 2.066±0.00 3.498±0.00 N/A 27.331±4.79 3.647±0.00 3.403±1.04 2.908±1.67 3.330±0.85 1.672±0.00 2.479±0.00 2.020±1.03 5.523±1.08 4.403±2.57 32.572±13.05
ENST00000393065 1.069±0.00 N/A 0.782±0.00 N/A 1.900±0.00 N/A 0.898±0.00 N/A 2.985±0.00 1.532±0.00 0.292±0.00 3.410±0.00 N/A N/A
ENST00000393066 N/A N/A 1.477±0.00 N/A N/A N/A N/A N/A 1.131±0.00 1.316±0.00 N/A N/A N/A 21.781±0.00
ENST00000577554 0.611±0.00 0.792±0.00 N/A N/A N/A N/A N/A N/A 0.553±0.00 1.312±0.00 N/A 0.954±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000566 CIL_000566_0002 CGP 17:58692573-58985176
CIL_000565 CIL_000565_0002 CGP 17:58755869-59106921

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003682 IEA chromatin binding
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005164 IPI tumor necrosis factor receptor binding
GO:0005515 IPI:IEA protein binding
GO:0005622 IEA intracellular
GO:0005737 IDA cytoplasm
GO:0005777 IDA peroxisome
GO:0005829 IDA cytosol
GO:0008270 IEA zinc ion binding
GO:0016235 IDA aggresome
GO:0016874 IEA ligase activity
GO:0031625 IPI ubiquitin protein ligase binding
GO:0032088 IDA negative regulation of NF-kappaB transcription factor activity
GO:0042803 IDA protein homodimerization activity
GO:0046600 IMP negative regulation of centriole replication
GO:0051091 IDA positive regulation of sequence-specific DNA binding transcription factor activity
GO:0051092 IDA positive regulation of NF-kappaB transcription factor activity
GO:0051865 IDA protein autoubiquitination
GO:0070842 IDA aggresome assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076473 trim37 tripartite motif containing 37 protein_coding Danio_rerio
ENSMUSG00000018548 Trim37 tripartite motif-containing 37 protein_coding Mus_musculus

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