C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Wolf-Hirschhorn syndrome candidate 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000109685 WHSC1 9606 + 4:1871424-1982207 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000312087 WHSC1-007 1892845-1982203 nonsense_mediated_decay
  ENST00000353275 WHSC1-002 1892782-1982203 nonsense_mediated_decay
  ENST00000382888 WHSC1-005 1952105-1978915 protein_coding
  ENST00000382891 WHSC1-201 1892782-1982206 protein_coding
  ENST00000382892 WHSC1-202 1892782-1982203 protein_coding
  ENST00000382895 WHSC1-008 1892845-1982207 protein_coding
  ENST00000398261 WHSC1-203 1900626-1948818 protein_coding
  ENST00000420906 WHSC1-006 1892845-1942575 protein_coding
  ENST00000436793 WHSC1-204 1900642-1912152 protein_coding
  ENST00000482415 WHSC1-003 1939281-1979796 processed_transcript
  ENST00000502425 WHSC1-023 1939752-1955221 processed_transcript
  ENST00000503128 WHSC1-004 1899218-1948818 protein_coding
  ENST00000503207 WHSC1-021 1953118-1956186 processed_transcript
  ENST00000505643 WHSC1-022 1952105-1956158 processed_transcript
  ENST00000507094 WHSC1-020 1955579-1958018 retained_intron
  ENST00000507820 WHSC1-013 1871434-1900766 protein_coding
  ENST00000508299 WHSC1-019 1976353-1978902 retained_intron
  ENST00000508355 WHSC1-009 1871454-1919187 retained_intron
  ENST00000508803 WHSC1-011 1871424-1978914 protein_coding
  ENST00000509115 WHSC1-015 1900619-1918389 protein_coding
  ENST00000511904 WHSC1-016 1918432-1951180 nonsense_mediated_decay
  ENST00000512700 WHSC1-012 1900650-1918199 nonsense_mediated_decay
  ENST00000513726 WHSC1-017 1930730-1953446 processed_transcript
  ENST00000514045 WHSC1-010 1871461-1941750 protein_coding
  ENST00000514329 WHSC1-024 1939661-1956188 protein_coding
  ENST00000515695 WHSC1-018 1974787-1975646 retained_intron
  ENST00000515806 WHSC1-014 1887501-1901251 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000312087ENST00000353275ENST00000382888ENST00000382891ENST00000382892ENST00000398261ENST00000420906ENST00000482415ENST00000503128ENST00000508355ENST00000508803ENST00000509115ENST00000511904ENST00000514045
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000312087 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.858±0.00 N/A N/A N/A
ENST00000353275 N/A N/A N/A N/A N/A N/A N/A 0.538±0.24 N/A N/A N/A N/A N/A N/A
ENST00000382888 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.612±0.00 N/A N/A
ENST00000382891 N/A 1.161±0.00 N/A N/A 1.707±0.00 2.916±0.00 1.203±0.55 0.957±0.00 0.736±0.00 N/A 0.337±0.00 3.614±1.35 4.139±1.77 7.503±0.00
ENST00000382892 N/A N/A N/A N/A N/A N/A N/A 1.298±0.00 N/A N/A N/A N/A 0.720±0.00 N/A
ENST00000398261 0.728±0.00 N/A 0.242±0.00 2.530±1.24 N/A 1.330±0.00 0.890±0.00 0.347±0.00 0.366±0.19 N/A 0.265±0.00 1.345±0.00 N/A 1.527±0.00
ENST00000420906 N/A N/A 0.320±0.00 2.020±0.00 N/A 1.800±0.00 N/A N/A 0.788±0.00 0.957±0.00 N/A N/A N/A N/A
ENST00000482415 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.187±0.00 N/A 3.191±0.00 N/A 5.663±0.00
ENST00000503128 N/A N/A 0.275±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000508355 N/A N/A 0.859±0.00 N/A N/A N/A N/A N/A N/A 1.295±0.00 N/A N/A N/A N/A
ENST00000508803 4.785±0.00 2.232±0.00 0.610±0.00 N/A 3.048±0.30 3.235±0.00 N/A N/A 1.370±0.80 2.150±0.00 2.662±0.00 2.688±0.00 N/A 17.586±10.97
ENST00000509115 N/A N/A N/A N/A N/A N/A 2.028±0.00 1.933±0.00 N/A N/A 1.054±0.00 N/A N/A N/A
ENST00000511904 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.180±0.00 N/A N/A N/A
ENST00000514045 N/A N/A N/A N/A N/A N/A 0.625±0.00 0.577±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007TX CIL_0007TX_0001 VISTA 4:1311752-1912379
CIL_0006V8 CIL_0006V8_0001 CGP 4:1811479-1982207
CIL_0006V9 CIL_0006V9_0001 CGP 4:1871424-2041903

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0003149 IEA membranous septum morphogenesis
GO:0003289 IEA atrial septum primum morphogenesis
GO:0003290 IEA atrial septum secundum morphogenesis
GO:0003677 IEA DNA binding
GO:0003682 IEA chromatin binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005694 IEA chromosome
GO:0005730 IDA nucleolus
GO:0005737 IEA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0008270 IEA zinc ion binding
GO:0009653 TAS anatomical structure morphogenesis
GO:0010452 IEA histone H3-K36 methylation
GO:0016568 IEA chromatin modification
GO:0018024 IEA histone-lysine N-methyltransferase activity
GO:0031965 IDA nuclear membrane
GO:0034770 IEA histone H4-K20 methylation
GO:0043565 IEA sequence-specific DNA binding
GO:0048298 IEA positive regulation of isotype switching to IgA isotypes
GO:0060348 IEA bone development
GO:0070201 IEA regulation of establishment of protein localization
GO:2001032 IEA regulation of double-strand break repair via nonhomologous end joining

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000026225 whsc1 Wolf-Hirschhorn syndrome candidate 1 protein_coding Danio_rerio
ENSMUSG00000057406 Whsc1 Wolf-Hirschhorn syndrome candidate 1 (human) protein_coding Mus_musculus

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