C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lactate dehydrogenase B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000111716 LDHB 9606 - 12:21635342-21757857 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000350669 LDHB-001 21635342-21657842 protein_coding
  ENST00000396075 LDHB-004 21638368-21657362 protein_coding
  ENST00000396076 LDHB-002 21635342-21657794 protein_coding
  ENST00000450584 LDHB-003 21643946-21657839 protein_coding
  ENST00000470280 LDHB-006 21643545-21654570 retained_intron
  ENST00000470985 LDHB-008 21635342-21638538 retained_intron
  ENST00000535112 LDHB-011 21654657-21757831 processed_transcript
  ENST00000539782 LDHB-010 21644050-21757857 protein_coding
  ENST00000542765 LDHB-009 21635342-21637374 retained_intron
  ENST00000544151 LDHB-007 21654355-21657971 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000350669ENST00000396075ENST00000470985ENST00000539782
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000350669 311.437±0.00 178.892±0.00 39.453±0.00 247.707±176.51 180.697±171.95 111.846±98.64 363.314±299.62 320.387±319.34 10.663±3.93 61.969±47.82 51.057±0.00 166.786±78.35 135.413±51.44 114.370±70.30
ENST00000396075 N/A N/A 181.643±0.00 229.412±0.00 31.681±0.00 52.622±0.00 224.255±0.00 17.664±0.00 94.590±0.00 53.825±0.00 56.153±0.00 110.262±5.97 113.863±0.00 32.405±0.00
ENST00000470985 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 125.893±0.00 N/A N/A
ENST00000539782 N/A N/A N/A N/A N/A N/A N/A 3.670±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005PS CIL_0005PS_0001 CGP 12:21536189-21757857
CIL_00090B CIL_00090B_0001 VISTA 12:21591137-22192666
CIL_0005PV CIL_0005PV_0001 CGP 12:21635342-21775581

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0004457 IEA lactate dehydrogenase activity
GO:0004459 IEA L-lactate dehydrogenase activity
GO:0005515 IPI protein binding
GO:0005737 IDA:IEA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005829 TAS cytosol
GO:0005975 IEA carbohydrate metabolic process
GO:0006089 IEA lactate metabolic process
GO:0006090 TAS pyruvate metabolic process
GO:0006096 IEA glycolytic process
GO:0016020 IDA membrane
GO:0016491 IEA oxidoreductase activity
GO:0016616 IEA oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0019674 IEA NAD metabolic process
GO:0019900 IEA kinase binding
GO:0042802 IEA identical protein binding
GO:0044237 TAS cellular metabolic process
GO:0044262 IEA cellular carbohydrate metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0051287 IEA NAD binding
GO:0055114 IEA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000019644 ldhba lactate dehydrogenase Ba protein_coding Danio_rerio
ENSDARG00000071076 ldhbb lactate dehydrogenase Bb protein_coding Danio_rerio
ENSMUSG00000030246 Ldhb lactate dehydrogenase B protein_coding Mus_musculus

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