C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transcription factor EB
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000112561 TFEB 9606 - 6:41683978-41736259 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000230323 TFEB-001 41683978-41735060 protein_coding
  ENST00000343317 TFEB-015 41683978-41691476 protein_coding
  ENST00000358871 TFEB-010 41683978-41736259 protein_coding
  ENST00000373033 TFEB-005 41683980-41735608 protein_coding
  ENST00000394283 TFEB-004 41686529-41733853 protein_coding
  ENST00000403298 TFEB-201 41683979-41734401 protein_coding
  ENST00000406563 TFEB-003 41683978-41691042 protein_coding
  ENST00000416140 TFEB-008 41687163-41723726 protein_coding
  ENST00000419396 TFEB-006 41687094-41734401 protein_coding
  ENST00000419574 TFEB-002 41687910-41705940 protein_coding
  ENST00000420312 TFEB-202 41683979-41735527 protein_coding
  ENST00000424495 TFEB-014 41690894-41733690 protein_coding
  ENST00000425401 TFEB-011 41691116-41735060 protein_coding
  ENST00000433032 TFEB-012 41691178-41734194 protein_coding
  ENST00000445214 TFEB-009 41691001-41705940 protein_coding
  ENST00000445700 TFEB-013 41691178-41733828 protein_coding
  ENST00000494822 TFEB-007 41687094-41688200 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000343317ENST00000358871ENST00000373033ENST00000394283ENST00000403298ENST00000406563ENST00000416140ENST00000419396ENST00000419574ENST00000420312ENST00000424495ENST00000494822
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000343317 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.719±0.00
ENST00000358871 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.578±0.00 11.276±4.22 N/A
ENST00000373033 6.598±0.00 7.900±0.00 N/A 4.029±3.40 4.636±0.00 12.710±0.00 5.399±4.53 5.244±5.07 1.370±0.00 5.134±4.78 26.463±22.11 5.860±4.41 4.798±1.44 4.017±0.00
ENST00000394283 N/A N/A 0.303±0.00 0.728±0.31 N/A 0.442±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000403298 N/A 11.732±0.00 N/A 2.950±0.00 N/A N/A N/A N/A 0.326±0.00 N/A N/A 1.381±0.00 16.161±0.00 2.310±0.00
ENST00000406563 N/A 6.351±0.00 N/A N/A N/A N/A N/A 2.646±0.00 N/A N/A N/A 4.755±1.16 10.723±3.35 N/A
ENST00000416140 N/A N/A N/A N/A N/A N/A 0.455±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000419396 N/A N/A 0.495±0.00 N/A N/A N/A N/A N/A 0.846±0.00 N/A 5.592±0.00 N/A N/A N/A
ENST00000419574 N/A N/A N/A N/A N/A 0.867±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000420312 N/A 6.962±0.00 N/A N/A 4.344±0.00 N/A N/A N/A 0.347±0.00 N/A N/A N/A 2.621±0.00 0.488±0.00
ENST00000424495 N/A N/A 3.093±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000494822 N/A N/A N/A N/A N/A N/A N/A 0.893±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008F3 CIL_0008F3_0001 VISTA 6:41112821-41713777
CIL_0007QG CIL_0007QG_0001 VISTA 6:41166717-41767957
CIL_0008IB CIL_0008IB_0001 VISTA 6:41169077-41770286
CIL_0008XI CIL_0008XI_0001 VISTA 6:41187113-41790491
CIL_00093V CIL_00093V_0001 VISTA 6:41255486-41855939
CIL_000963 CIL_000963_0001 VISTA 6:41292979-41894337
CIL_00028Y CIL_00028Y_0002 CGP 6:41636882-41736259

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001892 ISS embryonic placenta development
GO:0003677 IEA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005634 IDA nucleus
GO:0005667 IEA transcription factor complex
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 NAS:IEA regulation of transcription, DNA-templated
GO:0006914 IEA autophagy
GO:0006959 IEA:ISS humoral immune response
GO:0007040 IMP lysosome organization
GO:0010508 IMP positive regulation of autophagy
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IEA protein heterodimerization activity
GO:0046983 IEA protein dimerization activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010794 tfeb transcription factor EB protein_coding Danio_rerio
ENSMUSG00000023990 Tfeb transcription factor EB protein_coding Mus_musculus

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