C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transcription factor EB
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000023990 Tfeb 10090 + 17:47737030-47792419 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000024786 Tfeb-001 47785720-47792415 protein_coding
  ENSMUST00000086932 Tfeb-002 47737030-47792419 protein_coding
  ENSMUST00000113284 Tfeb-011 47738903-47789070 protein_coding
  ENSMUST00000113288 Tfeb-003 47737928-47792415 protein_coding
  ENSMUST00000124765 Tfeb-008 47787568-47789716 processed_transcript
  ENSMUST00000125177 Tfeb-004 47759175-47786196 protein_coding
  ENSMUST00000126258 Tfeb-010 47737600-47786084 protein_coding
  ENSMUST00000130208 Tfeb-005 47763170-47786297 protein_coding
  ENSMUST00000137845 Tfeb-012 47754326-47786084 protein_coding
  ENSMUST00000140715 Tfeb-007 47789441-47791613 retained_intron
  ENSMUST00000141631 Tfeb-006 47782875-47786377 protein_coding
  ENSMUST00000146782 Tfeb-009 47786155-47792416 protein_coding
  ENSMUST00000159641 Tfeb-013 47769238-47786301 protein_coding
  ENSMUST00000160373 Tfeb-014 47769238-47786299 protein_coding
  ENSMUST00000162719 Tfeb-015 47787910-47788938 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000024786ENSMUST00000086932ENSMUST00000124765ENSMUST00000146782ENSMUST00000160373ENSMUST00000162719
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000024786 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 15.591±9.18 0.459±0.21
ENSMUST00000086932 5.152±1.41 11.990±0.94 6.504±0.45 0.950±0.19 15.766±2.51 14.720±0.86 10.139±1.20 11.885±0.70 3.280±0.98 12.842±1.38 13.942±6.22 7.998±3.32 4.663±0.34 1.417±0.61
ENSMUST00000124765 N/A N/A N/A 8.056±0.00 N/A N/A N/A N/A N/A N/A N/A 17.921±0.00 85.366±34.81 6.299±0.00
ENSMUST00000146782 N/A N/A N/A 2.112±0.00 N/A N/A N/A N/A N/A N/A 14.256±1.83 1.490±0.46 12.163±3.53 0.495±0.00
ENSMUST00000160373 N/A 31.830±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000162719 N/A N/A N/A N/A 2.201±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000963 CIL_000963_0002 VISTA 17:47571879-48173076
CIL_00093V CIL_00093V_0002 VISTA 17:47614773-48215356
CIL_0008XI CIL_0008XI_0002 VISTA 17:47688296-48291797
CIL_0008IB CIL_0008IB_0002 VISTA 17:47708185-48309224
CIL_0007QG CIL_0007QG_0002 VISTA 17:47710565-48311720

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001892 IMP embryonic placenta development
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005634 ISS nucleus
GO:0005667 IDA transcription factor complex
GO:0005737 ISS cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006914 IEA autophagy
GO:0006959 IEA:IMP humoral immune response
GO:0007040 ISS lysosome organization
GO:0010508 ISS positive regulation of autophagy
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IPI protein heterodimerization activity
GO:0046983 IEA protein dimerization activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010794 tfeb transcription factor EB protein_coding Danio_rerio
ENSG00000112561 TFEB transcription factor EB protein_coding Homo_sapiens

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