C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: eukaryotic translation initiation factor 4 gamma, 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000114867 EIF4G1 9606 + 3:184314495-184335358 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000319274 EIF4G1-201 184320313-184335351 protein_coding
  ENST00000342981 EIF4G1-001 184315166-184335358 protein_coding
  ENST00000346169 EIF4G1-007 184314495-184335353 protein_coding
  ENST00000350481 EIF4G1-009 184314606-184335353 protein_coding
  ENST00000352767 EIF4G1-202 184314495-184335357 protein_coding
  ENST00000382330 EIF4G1-014 184314567-184335017 protein_coding
  ENST00000392537 EIF4G1-003 184314542-184335351 protein_coding
  ENST00000411531 EIF4G1-038 184316192-184334908 protein_coding
  ENST00000413967 EIF4G1-004 184314568-184325299 nonsense_mediated_decay
  ENST00000414031 EIF4G1-010 184314502-184335353 protein_coding
  ENST00000421110 EIF4G1-006 184314562-184324312 protein_coding
  ENST00000422614 EIF4G1-034 184327949-184332086 nonsense_mediated_decay
  ENST00000424196 EIF4G1-013 184315408-184335351 protein_coding
  ENST00000426123 EIF4G1-005 184314569-184325299 protein_coding
  ENST00000427141 EIF4G1-023 184314654-184319801 protein_coding
  ENST00000427607 EIF4G1-028 184320446-184321661 protein_coding
  ENST00000427845 EIF4G1-012 184315164-184334908 protein_coding
  ENST00000428387 EIF4G1-027 184320297-184321603 protein_coding
  ENST00000434061 EIF4G1-016 184320313-184335351 protein_coding
  ENST00000435046 EIF4G1-041 184320664-184335347 protein_coding
  ENST00000440448 EIF4G1-022 184314619-184319728 protein_coding
  ENST00000441154 EIF4G1-039 184319757-184334908 protein_coding
  ENST00000442406 EIF4G1-002 184314551-184335353 nonsense_mediated_decay
  ENST00000444134 EIF4G1-037 184314550-184321554 protein_coding
  ENST00000444861 EIF4G1-015 184319199-184325021 protein_coding
  ENST00000448284 EIF4G1-031 184325104-184327303 protein_coding
  ENST00000450424 EIF4G1-008 184314552-184324226 protein_coding
  ENST00000455679 EIF4G1-020 184314608-184317773 protein_coding
  ENST00000456033 EIF4G1-024 184315763-184320722 protein_coding
  ENST00000457456 EIF4G1-029 184320461-184322027 protein_coding
  ENST00000460829 EIF4G1-017 184328117-184335054 retained_intron
  ENST00000464548 EIF4G1-036 184328669-184331853 retained_intron
  ENST00000466311 EIF4G1-032 184325299-184326908 retained_intron
  ENST00000475721 EIF4G1-018 184328616-184335317 retained_intron
  ENST00000478291 EIF4G1-035 184331314-184332105 retained_intron
  ENST00000482303 EIF4G1-033 184327286-184327915 retained_intron
  ENST00000484862 EIF4G1-025 184319625-184321534 retained_intron
  ENST00000485712 EIF4G1-021 184314613-184316117 retained_intron
  ENST00000493299 EIF4G1-030 184320485-184321507 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000342981ENST00000346169ENST00000350481ENST00000382330ENST00000392537ENST00000411531ENST00000427845ENST00000435046ENST00000441154ENST00000442406ENST00000444861ENST00000475721
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000342981 N/A N/A N/A N/A N/A N/A N/A 2.759±0.00 N/A N/A N/A N/A N/A N/A
ENST00000346169 N/A N/A 2.694±0.00 N/A N/A 6.579±0.00 N/A 5.292±0.00 3.349±0.00 2.715±0.00 N/A 12.864±4.83 7.913±0.89 N/A
ENST00000350481 N/A N/A N/A N/A N/A N/A N/A N/A 3.073±0.00 N/A N/A N/A N/A N/A
ENST00000382330 12.844±0.00 N/A 3.315±0.00 5.861±3.34 8.774±2.00 10.190±0.00 7.556±4.25 7.234±2.03 12.904±0.00 8.266±3.46 23.663±17.57 14.941±1.22 7.881±0.75 10.882±0.00
ENST00000392537 N/A N/A N/A N/A 4.511±0.00 N/A N/A N/A 3.799±0.00 N/A N/A N/A N/A N/A
ENST00000411531 N/A N/A 3.516±0.00 4.346±0.00 8.078±0.00 8.228±0.00 13.676±9.21 9.285±2.29 9.662±1.83 10.510±5.17 44.761±37.99 19.814±0.00 13.700±2.41 N/A
ENST00000427845 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.747±0.00 N/A N/A N/A
ENST00000435046 17.358±0.00 28.526±0.00 N/A 14.900±0.00 21.761±0.00 9.613±0.00 20.620±0.00 12.236±0.00 16.140±0.00 14.980±0.00 69.568±0.00 42.865±23.68 26.866±7.78 22.069±3.11
ENST00000441154 22.667±0.00 19.270±0.00 N/A 14.678±0.00 19.691±0.00 15.534±0.00 N/A 25.604±0.00 16.161±0.00 12.466±0.00 N/A 40.319±5.07 20.883±0.00 23.991±0.53
ENST00000442406 N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.051±0.00 N/A N/A N/A N/A
ENST00000444861 N/A N/A 3.350±0.00 N/A N/A N/A N/A 5.652±0.00 N/A N/A N/A N/A N/A N/A
ENST00000475721 53.910±0.00 92.341±0.00 N/A N/A 58.781±0.00 48.206±0.00 N/A 76.599±0.00 89.258±0.00 62.562±0.00 153.464±0.00 173.498±145.97 73.818±48.54 82.068±26.62

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005G3 CIL_0005G3_0001 CGP 3:184135038-184684758
CIL_000572 CIL_000572_0001 CGP 3:184298709-184335358
CIL_00056Z CIL_00056Z_0001 CGP 3:184314495-184346275

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000184 TAS nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000288 TAS nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000289 TAS nuclear-transcribed mRNA poly(A) tail shortening
GO:0003723 IEA RNA binding
GO:0003743 TAS translation initiation factor activity
GO:0005488 IEA binding
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005829 TAS cytosol
GO:0006412 TAS translation
GO:0006413 TAS translational initiation
GO:0006446 IMP regulation of translational initiation
GO:0008135 TAS translation factor activity, nucleic acid binding
GO:0008219 IEA cell death
GO:0008286 TAS insulin receptor signaling pathway
GO:0010467 TAS gene expression
GO:0016020 IDA membrane
GO:0016032 IEA viral process
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0044267 TAS cellular protein metabolic process
GO:0044822 IDA poly(A) RNA binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000006200 EIF4G1 (1 of 3) eukaryotic translation initiation factor 4 gamma, 1 protein_coding Danio_rerio
ENSDARG00000075801 EIF4G1 (2 of 3) eukaryotic translation initiation factor 4 gamma, 1 protein_coding Danio_rerio
ENSDARG00000077766 CABZ01085054.1 Uncharacterized protein protein_coding Danio_rerio
ENSMUSG00000045983 Eif4g1 eukaryotic translation initiation factor 4, gamma 1 protein_coding Mus_musculus

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