C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phosphoinositide kinase, FYVE finger containing
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000115020 PIKFYVE 9606 + 2:208266267-208358751 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000264380 PIKFYVE-001 208266267-208358751 protein_coding
  ENST00000308862 PIKFYVE-005 208266278-208305128 protein_coding
  ENST00000392202 PIKFYVE-002 208266267-208305549 protein_coding
  ENST00000407449 PIKFYVE-004 208266278-208305128 protein_coding
  ENST00000422495 PIKFYVE-009 208266357-208285800 protein_coding
  ENST00000443896 PIKFYVE-003 208266267-208326107 nonsense_mediated_decay
  ENST00000452564 PIKFYVE-006 208266363-208335856 protein_coding
  ENST00000474721 PIKFYVE-008 208334372-208336865 processed_transcript
  ENST00000477200 PIKFYVE-007 208298641-208302580 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000264380ENST00000392202ENST00000443896ENST00000452564
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000264380 1.260±0.00 0.757±0.00 1.736±0.00 0.569±0.00 2.185±1.44 0.778±0.24 1.125±0.00 1.101±0.00 N/A 1.100±0.43 1.272±0.91 0.403±0.06 3.257±1.72
ENST00000392202 N/A N/A 4.383±0.00 N/A N/A 4.664±0.00 N/A N/A 4.746±0.00 N/A 6.422±0.00 N/A N/A
ENST00000443896 N/A N/A 1.526±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000452564 N/A N/A N/A N/A N/A N/A 0.764±0.00 N/A 2.662±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00014C CIL_00014C_0001 CGP 2:208236227-208358751
CIL_0006P3 CIL_0006P3_0001 CGP 2:208266267-208854503

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000139 TAS Golgi membrane
GO:0000285 IEA 1-phosphatidylinositol-3-phosphate 5-kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005829 IEA cytosol
GO:0005911 IEA cell-cell junction
GO:0006644 TAS phospholipid metabolic process
GO:0006661 TAS phosphatidylinositol biosynthetic process
GO:0010008 IDA endosome membrane
GO:0016307 IEA phosphatidylinositol phosphate kinase activity
GO:0016308 TAS 1-phosphatidylinositol-4-phosphate 5-kinase activity
GO:0031410 IEA cytoplasmic vesicle
GO:0031901 IDA early endosome membrane
GO:0031902 TAS late endosome membrane
GO:0032288 IEA myelin assembly
GO:0034504 IMP protein localization to nucleus
GO:0035556 IEA intracellular signal transduction
GO:0036092 TAS phosphatidylinositol-3-phosphate biosynthetic process
GO:0042147 IMP retrograde transport, endosome to Golgi
GO:0043813 TAS phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity
GO:0044267 IEA cellular protein metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045121 IDA membrane raft
GO:0046488 IEA phosphatidylinositol metabolic process
GO:0046854 IEA phosphatidylinositol phosphorylation
GO:0046872 IEA metal ion binding
GO:0048471 IEA perinuclear region of cytoplasm

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000056112 pikfyve phosphoinositide kinase, FYVE finger containing protein_coding Danio_rerio
ENSMUSG00000025949 Pikfyve phosphoinositide kinase, FYVE finger containing protein_coding Mus_musculus

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