C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: phosphoinositide kinase, FYVE finger containing
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000392202 PIKFYVE-002 ENSG00000115020 9606 + 2:208266267-208305549 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderColonLiverOvaryENST00000392202
Transcript ID Bladder Colon Liver Ovary
ENST00000392202 4.383±0.00 4.664±0.00 4.746±0.00 6.422±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00014C CIL_00014C_0001 CGP 2:208236227-208358751
CIL_0006P3 CIL_0006P3_0001 CGP 2:208266267-208854503

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000139 TAS Golgi membrane
GO:0000285 IEA 1-phosphatidylinositol-3-phosphate 5-kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0006644 TAS phospholipid metabolic process
GO:0006661 TAS phosphatidylinositol biosynthetic process
GO:0010008 IDA endosome membrane
GO:0016308 TAS 1-phosphatidylinositol-4-phosphate 5-kinase activity
GO:0031901 IDA early endosome membrane
GO:0031902 TAS late endosome membrane
GO:0034504 IMP protein localization to nucleus
GO:0035556 IEA intracellular signal transduction
GO:0036092 TAS phosphatidylinositol-3-phosphate biosynthetic process
GO:0042147 IMP retrograde transport, endosome to Golgi
GO:0043813 TAS phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity
GO:0044267 IEA cellular protein metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045121 IDA membrane raft
GO:0046854 IEA phosphatidylinositol phosphorylation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000097707 Pikfyve-006 protein_coding Mus_musculus 0 1517
ENSMUST00000186404 Pikfyve-005 retained_intron Mus_musculus 0 1517
ENSMUST00000190058 Pikfyve-007 nonsense_mediated_decay Mus_musculus 0 1517
ENSMUST00000081154 Pikfyve-001 protein_coding Mus_musculus 0 1219
ENSMUST00000188799 Pikfyve-010 retained_intron Mus_musculus 0 1218
ENSMUST00000190847 Pikfyve-009 retained_intron Mus_musculus 0 625
ENSMUST00000189925 Pikfyve-004 processed_transcript Mus_musculus 0 416
ENSMUST00000185317 Pikfyve-002 retained_intron Mus_musculus 0 416
ENSMUST00000185263 Pikfyve-008 nonsense_mediated_decay Mus_musculus 0 281
ENSMUST00000187579 Pikfyve-003 retained_intron Mus_musculus 0 237

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