C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phosphoinositide kinase, FYVE finger containing
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025949 Pikfyve 10090 + 1:65186683-65278695 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000081154 Pikfyve-001 65186702-65278695 protein_coding
  ENSMUST00000097707 Pikfyve-006 65186750-65274012 protein_coding
  ENSMUST00000185263 Pikfyve-008 65186713-65192187 nonsense_mediated_decay
  ENSMUST00000185317 Pikfyve-002 65186683-65205706 retained_intron
  ENSMUST00000186404 Pikfyve-005 65186704-65233284 retained_intron
  ENSMUST00000187579 Pikfyve-003 65186694-65192483 retained_intron
  ENSMUST00000188799 Pikfyve-010 65186693-65226117 retained_intron
  ENSMUST00000189925 Pikfyve-004 65186696-65206174 processed_transcript
  ENSMUST00000190058 Pikfyve-007 65186689-65246898 nonsense_mediated_decay
  ENSMUST00000190847 Pikfyve-009 65196760-65216262 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000081154ENSMUST00000097707ENSMUST00000185263ENSMUST00000185317ENSMUST00000186404ENSMUST00000190058
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000081154 1.441±0.32 1.414±0.45 0.851±0.57 3.936±0.34 1.742±0.81 1.116±0.31 0.267±0.05 0.695±0.15 0.568±0.46 1.032±0.33 0.292±0.10 1.623±0.95 0.837±0.28 0.682±0.35
ENSMUST00000097707 1.568±0.39 N/A N/A N/A 1.600±1.22 N/A 0.554±0.19 0.649±0.00 0.577±0.13 N/A N/A 1.790±0.48 1.393±0.15 0.873±0.22
ENSMUST00000185263 N/A 5.928±1.64 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000185317 N/A 2.920±0.00 N/A N/A 5.911±0.00 1.900±0.12 N/A N/A N/A 3.758±0.00 N/A 3.098±0.00 N/A N/A
ENSMUST00000186404 N/A 1.112±0.23 N/A N/A N/A 0.696±0.07 N/A N/A 0.538±0.03 N/A N/A 1.044±0.05 N/A N/A
ENSMUST00000190058 N/A 0.949±0.09 N/A N/A 1.863±0.60 0.876±0.10 N/A N/A N/A N/A N/A 1.962±0.58 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00014C CIL_00014C_0002 CGP 1:65158616-65278695
CIL_0006P3 CIL_0006P3_0002 CGP 1:65186683-65389244

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000139 TAS Golgi membrane
GO:0000285 TAS 1-phosphatidylinositol-3-phosphate 5-kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005829 IDA cytosol
GO:0005911 IDA cell-cell junction
GO:0008270 IDA zinc ion binding
GO:0010008 IEA endosome membrane
GO:0012506 IDA vesicle membrane
GO:0016307 IEA phosphatidylinositol phosphate kinase activity
GO:0016308 IDA 1-phosphatidylinositol-4-phosphate 5-kinase activity
GO:0031410 IDA cytoplasmic vesicle
GO:0031901 IEA early endosome membrane
GO:0031902 TAS late endosome membrane
GO:0032288 IGI myelin assembly
GO:0034504 IEA protein localization to nucleus
GO:0035556 IEA intracellular signal transduction
GO:0042147 IEA retrograde transport, endosome to Golgi
GO:0044267 IEA cellular protein metabolic process
GO:0045121 IEA membrane raft
GO:0046854 IEA phosphatidylinositol phosphorylation
GO:0046872 IEA metal ion binding
GO:0048471 IDA perinuclear region of cytoplasm
GO:0052810 TAS 1-phosphatidylinositol-5-kinase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000056112 pikfyve phosphoinositide kinase, FYVE finger containing protein_coding Danio_rerio
ENSG00000115020 PIKFYVE phosphoinositide kinase, FYVE finger containing protein_coding Homo_sapiens

Loading