C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: fibronectin 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000115414 FN1 9606 - 2:215360440-215436172 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000323926 FN1-002 215360454-215436068 protein_coding
  ENST00000336916 FN1-003 215360454-215436068 protein_coding
  ENST00000354785 FN1-001 215360454-215436172 protein_coding
  ENST00000356005 FN1-013 215360866-215436068 protein_coding
  ENST00000357867 FN1-004 215360454-215436068 protein_coding
  ENST00000359671 FN1-201 215360458-215436068 protein_coding
  ENST00000421182 FN1-005 215360440-215436067 protein_coding
  ENST00000426059 FN1-014 215414661-215436073 protein_coding
  ENST00000432072 FN1-012 215360865-215436067 protein_coding
  ENST00000438981 FN1-026 215371909-215375689 protein_coding
  ENST00000443816 FN1-009 215360862-215436073 protein_coding
  ENST00000446046 FN1-008 215360862-215436068 protein_coding
  ENST00000456923 FN1-011 215361147-215393147 protein_coding
  ENST00000460217 FN1-025 215371864-215375725 retained_intron
  ENST00000461974 FN1-022 215370343-215372482 retained_intron
  ENST00000469569 FN1-018 215364370-215365517 retained_intron
  ENST00000471193 FN1-031 215408319-215409950 retained_intron
  ENST00000473614 FN1-019 215364667-215365753 retained_intron
  ENST00000474036 FN1-027 215375633-215381329 retained_intron
  ENST00000480024 FN1-021 215367679-215370520 retained_intron
  ENST00000480737 FN1-024 215382159-215384080 retained_intron
  ENST00000485567 FN1-023 215370380-215372439 retained_intron
  ENST00000490833 FN1-028 215379205-215383483 processed_transcript
  ENST00000492816 FN1-007 215360862-215393721 retained_intron
  ENST00000494446 FN1-017 215361341-215365676 retained_intron
  ENST00000496542 FN1-032 215419289-215421270 retained_intron
  ENST00000498719 FN1-010 215360866-215363640 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000323926ENST00000356005ENST00000357867ENST00000426059ENST00000432072ENST00000443816ENST00000446046ENST00000456923
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000323926 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 13.348±0.00 N/A N/A
ENST00000356005 N/A N/A 6.026±0.00 N/A 12.821±0.00 15.393±0.00 5.751±0.00 N/A 48.115±0.00 42.450±0.00 N/A 30.409±0.00 N/A N/A
ENST00000357867 N/A N/A N/A N/A N/A N/A N/A 98.142±0.00 N/A N/A N/A N/A N/A N/A
ENST00000426059 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 22.357±0.00 N/A 4.815±0.00
ENST00000432072 N/A N/A N/A N/A N/A N/A 5.057±0.00 5.671±0.00 N/A N/A N/A 17.362±0.38 532.882±345.76 N/A
ENST00000443816 23.409±0.00 5.381±0.00 5.593±0.00 7.898±4.81 25.958±2.62 20.418±0.00 11.053±4.56 371.944±0.00 49.848±0.16 85.582±23.06 5.022±0.44 N/A 684.662±518.11 31.009±0.00
ENST00000446046 12.563±0.00 15.248±0.00 N/A 5.434±4.30 14.160±2.10 29.961±20.23 10.041±0.00 17.150±0.00 41.913±3.03 101.636±79.13 N/A 27.257±12.63 1170.402±605.46 8.003±6.19
ENST00000456923 18.572±0.00 18.413±0.00 N/A 2.637±0.00 28.653±0.00 69.468±0.00 17.078±0.00 22.346±0.00 89.263±0.00 254.989±0.00 3.477±0.25 71.709±43.96 2232.314±1116.58 17.480±9.74

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005MI CIL_0005MI_0001 CGP 2:215311817-215436172
CIL_0005MJ CIL_0005MJ_0001 CGP 2:215360440-216034096

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0002020 IPI protease binding
GO:0002576 TAS platelet degranulation
GO:0005178 IDA integrin binding
GO:0005515 IPI:IEA protein binding
GO:0005518 NAS collagen binding
GO:0005576 NAS:IEA extracellular region
GO:0005577 IDA fibrinogen complex
GO:0005604 IEA basement membrane
GO:0005605 IEA basal lamina
GO:0005615 IDA extracellular space
GO:0005793 IDA endoplasmic reticulum-Golgi intermediate compartment
GO:0006953 IEA acute-phase response
GO:0007044 IEA cell-substrate junction assembly
GO:0007155 NAS cell adhesion
GO:0007160 IEA cell-matrix adhesion
GO:0007161 IEA calcium-independent cell-matrix adhesion
GO:0007596 TAS blood coagulation
GO:0008201 NAS heparin binding
GO:0008360 IEA regulation of cell shape
GO:0009611 NAS response to wounding
GO:0010952 IEA positive regulation of peptidase activity
GO:0016324 IEA apical plasma membrane
GO:0016504 IEA peptidase activator activity
GO:0018149 IDA peptide cross-linking
GO:0022617 TAS extracellular matrix disassembly
GO:0030168 TAS platelet activation
GO:0030198 TAS extracellular matrix organization
GO:0031012 IDA extracellular matrix
GO:0031093 TAS platelet alpha granule lumen
GO:0033622 IMP integrin activation
GO:0034446 IDA substrate adhesion-dependent cell spreading
GO:0035987 IDA endodermal cell differentiation
GO:0042060 IEA wound healing
GO:0045773 IEA positive regulation of axon extension
GO:0050900 TAS leukocyte migration
GO:0070062 IDA extracellular vesicular exosome
GO:0072562 IDA blood microparticle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000006526 fn1b fibronectin 1b protein_coding Danio_rerio
ENSDARG00000019815 fn1a fibronectin 1a protein_coding Danio_rerio
ENSMUSG00000026193 Fn1 fibronectin 1 protein_coding Mus_musculus

Loading