C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: fibronectin 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026193 Fn1 10090 - 1:71585520-71653200 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000055226 Fn1-001 71585524-71653175 protein_coding
  ENSMUST00000185408 Fn1-012 71585526-71609567 retained_intron
  ENSMUST00000186129 Fn1-002 71585524-71653200 protein_coding
  ENSMUST00000186575 Fn1-018 71586861-71591071 retained_intron
  ENSMUST00000186613 Fn1-014 71629457-71641288 nonsense_mediated_decay
  ENSMUST00000186736 Fn1-013 71645643-71653172 protein_coding
  ENSMUST00000186879 Fn1-009 71644477-71653172 retained_intron
  ENSMUST00000186940 Fn1-010 71642825-71653161 protein_coding
  ENSMUST00000186985 Fn1-016 71598360-71602376 nonsense_mediated_decay
  ENSMUST00000187627 Fn1-017 71590097-71600368 nonsense_mediated_decay
  ENSMUST00000187938 Fn1-007 71585523-71653172 protein_coding
  ENSMUST00000188092 Fn1-015 71600387-71602844 retained_intron
  ENSMUST00000188674 Fn1-005 71585523-71653172 protein_coding
  ENSMUST00000188894 Fn1-003 71585520-71653172 protein_coding
  ENSMUST00000189160 Fn1-011 71604097-71624344 retained_intron
  ENSMUST00000189821 Fn1-006 71585523-71653172 protein_coding
  ENSMUST00000190780 Fn1-008 71585524-71653172 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000055226ENSMUST00000185408ENSMUST00000186129ENSMUST00000186940ENSMUST00000186985ENSMUST00000187627ENSMUST00000187938ENSMUST00000188894ENSMUST00000189160ENSMUST00000189821ENSMUST00000190780
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000055226 38.464±27.25 1.489±0.32 30.810±3.31 13.504±1.71 37.106±7.22 14.402±1.17 N/A N/A 9.095±2.31 N/A N/A 20.011±4.72 39.445±0.00 1.085±0.34
ENSMUST00000185408 32.189±4.13 N/A 80.353±25.22 7.269±0.00 N/A N/A N/A N/A 13.682±3.60 N/A 1.572±0.02 15.741±0.00 179.599±0.00 N/A
ENSMUST00000186129 47.068±0.92 N/A 82.297±12.50 4.165±0.00 96.936±9.39 24.483±4.52 7.093±0.98 7.578±0.99 48.955±50.26 24.380±1.23 2.208±0.58 16.396±3.19 N/A 1.325±0.04
ENSMUST00000186940 N/A N/A N/A 13.920±0.00 N/A N/A N/A N/A N/A N/A N/A 80.870±0.00 497.828±0.00 4.301±0.00
ENSMUST00000186985 N/A 16.150±3.38 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000187627 N/A N/A N/A 16.570±0.00 N/A N/A N/A N/A N/A N/A N/A 129.658±0.00 1731.364±1097.51 6.311±0.00
ENSMUST00000187938 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 167.935±116.02 N/A
ENSMUST00000188894 59.108±46.91 1.855±0.47 47.266±7.63 4.109±0.00 N/A 18.969±2.45 2.326±0.53 5.694±1.27 N/A 16.969±3.41 N/A 32.029±9.58 186.321±137.11 2.478±1.07
ENSMUST00000189160 N/A 4.045±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000189821 N/A 3.059±0.85 N/A N/A N/A N/A N/A N/A 77.149±33.75 N/A N/A N/A 236.784±6.74 0.366±0.00
ENSMUST00000190780 29.107±10.03 2.706±0.55 N/A 2.105±0.00 45.533±10.04 16.301±1.79 3.815±0.76 3.410±0.46 59.837±40.98 20.545±2.92 1.679±0.20 14.442±2.93 202.140±214.32 0.642±0.07

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005MI CIL_0005MI_0002 CGP 1:71557150-71653200
CIL_0005MJ CIL_0005MJ_0002 CGP 1:71585520-72212307

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0002020 IEA protease binding
GO:0005178 IEA integrin binding
GO:0005515 IPI protein binding
GO:0005577 IEA fibrinogen complex
GO:0005578 TAS proteinaceous extracellular matrix
GO:0005604 IDA basement membrane
GO:0005605 IDA basal lamina
GO:0005615 IEA extracellular space
GO:0005793 IEA endoplasmic reticulum-Golgi intermediate compartment
GO:0006953 IEA acute-phase response
GO:0007044 IDA cell-substrate junction assembly
GO:0007155 IDA cell adhesion
GO:0007160 IDA cell-matrix adhesion
GO:0007161 IDA calcium-independent cell-matrix adhesion
GO:0008201 IEA heparin binding
GO:0008360 IEA regulation of cell shape
GO:0010952 IDA positive regulation of peptidase activity
GO:0016324 IDA apical plasma membrane
GO:0016504 IDA peptidase activator activity
GO:0018149 IEA peptide cross-linking
GO:0031012 IDA extracellular matrix
GO:0033622 IEA integrin activation
GO:0034446 IEA substrate adhesion-dependent cell spreading
GO:0035987 IEA endodermal cell differentiation
GO:0042060 IMP wound healing
GO:0045773 IDA positive regulation of axon extension
GO:0070062 IEA extracellular vesicular exosome
GO:0072562 IEA blood microparticle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000006526 fn1b fibronectin 1b protein_coding Danio_rerio
ENSDARG00000019815 fn1a fibronectin 1a protein_coding Danio_rerio
ENSG00000115414 FN1 fibronectin 1 protein_coding Homo_sapiens

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