C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phosphoenolpyruvate carboxykinase 1 (soluble)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000124253 PCK1 9606 + 20:57561080-57568112 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000319441 PCK1-001 57561080-57568112 protein_coding
  ENST00000467047 PCK1-002 57561080-57566367 retained_intron
  ENST00000470051 PCK1-005 57562834-57563591 retained_intron
  ENST00000475833 PCK1-003 57561103-57562307 retained_intron
  ENST00000485958 PCK1-006 57564084-57565392 retained_intron
  ENST00000498194 PCK1-004 57562348-57563607 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000319441ENST00000467047ENST00000470051ENST00000475833ENST00000485958ENST00000498194
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000319441 0.097±0.00 27.480±0.00 0.084±0.01 2.165±0.00 10.707±0.00 0.189±0.00 26.186±0.00 2.644±0.00 0.326±0.16 0.197±0.09 0.270±0.15 0.107±0.06 0.271±0.02
ENST00000467047 N/A 9.349±0.00 N/A 0.480±0.00 6.421±0.00 0.110±0.09 8.731±0.00 1.058±0.00 0.176±0.00 N/A 0.135±0.00 N/A N/A
ENST00000470051 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.150±0.00 N/A N/A
ENST00000475833 N/A N/A N/A N/A N/A N/A N/A 2.553±0.00 0.470±0.00 N/A N/A N/A N/A
ENST00000485958 N/A N/A N/A N/A N/A 0.314±0.00 N/A N/A N/A 0.178±0.00 0.413±0.00 0.196±0.00 N/A
ENST00000498194 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.052±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008HJ CIL_0008HJ_0001 VISTA 20:57109440-57710361
CIL_0008BA CIL_0008BA_0001 VISTA 20:57139654-57744237
CIL_0005JC CIL_0005JC_0001 CGP 20:57495966-57568112
CIL_0005K4 CIL_0005K4_0001 CGP 20:57561080-57620576

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 IDA magnesium ion binding
GO:0004611 IEA phosphoenolpyruvate carboxykinase activity
GO:0004613 ISS phosphoenolpyruvate carboxykinase (GTP) activity
GO:0005525 IDA:IEA GTP binding
GO:0005737 ISS cytoplasm
GO:0005829 TAS cytosol
GO:0005975 TAS carbohydrate metabolic process
GO:0006006 IMP glucose metabolic process
GO:0006094 ISS:IEA gluconeogenesis
GO:0006107 IEA oxaloacetate metabolic process
GO:0006475 IDA internal protein amino acid acetylation
GO:0006629 IEA lipid metabolic process
GO:0014823 IEA response to activity
GO:0017076 IEA purine nucleotide binding
GO:0017144 TAS drug metabolic process
GO:0019003 IEA GDP binding
GO:0030145 IDA manganese ion binding
GO:0031406 IDA carboxylic acid binding
GO:0032868 IDA response to insulin
GO:0042593 ISS glucose homeostasis
GO:0044281 TAS small molecule metabolic process
GO:0046327 ISS glycerol biosynthetic process from pyruvate
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013522 pck1 phosphoenolpyruvate carboxykinase 1 (soluble) protein_coding Danio_rerio
ENSMUSG00000027513 Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic protein_coding Mus_musculus

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