C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: polymerase (RNA) I polypeptide B, 128kDa
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000125630 POLR1B 9606 + 2:112541915-112577150 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000263331 POLR1B-001 112541915-112576299 protein_coding
  ENST00000333990 POLR1B-002 112542189-112576299 nonsense_mediated_decay
  ENST00000409894 POLR1B-003 112542226-112577058 protein_coding
  ENST00000417433 POLR1B-005 112542465-112576295 protein_coding
  ENST00000424062 POLR1B-009 112542450-112549358 nonsense_mediated_decay
  ENST00000430293 POLR1B-008 112542419-112551979 nonsense_mediated_decay
  ENST00000430769 POLR1B-006 112542036-112547176 protein_coding
  ENST00000438748 POLR1B-007 112542019-112547461 protein_coding
  ENST00000448770 POLR1B-004 112542274-112576029 nonsense_mediated_decay
  ENST00000458012 POLR1B-015 112564362-112575089 protein_coding
  ENST00000468475 POLR1B-011 112546934-112550908 retained_intron
  ENST00000475318 POLR1B-012 112550707-112552804 retained_intron
  ENST00000484574 POLR1B-014 112564314-112572598 retained_intron
  ENST00000496238 POLR1B-010 112542675-112549360 processed_transcript
  ENST00000498054 POLR1B-013 112553385-112559395 processed_transcript
  ENST00000537335 POLR1B-201 112541915-112577150 protein_coding
  ENST00000541869 POLR1B-202 112542036-112577150 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000263331ENST00000333990ENST00000409894ENST00000417433ENST00000448770ENST00000458012ENST00000484574ENST00000537335ENST00000541869
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000263331 N/A N/A N/A N/A N/A N/A N/A N/A 0.366±0.00 N/A N/A 1.580±0.00 0.887±0.00 2.030±0.00
ENST00000333990 N/A 1.868±0.00 N/A N/A N/A N/A 0.203±0.05 N/A N/A N/A N/A N/A N/A N/A
ENST00000409894 N/A N/A 0.324±0.00 0.550±0.00 N/A 0.345±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000417433 0.398±0.00 0.880±0.00 N/A 0.639±0.00 1.041±0.53 1.436±0.41 0.735±0.00 3.749±0.00 1.178±0.71 0.914±0.00 2.724±0.00 1.963±0.25 0.972±0.35 1.876±0.00
ENST00000448770 0.600±0.00 1.600±0.00 0.763±0.00 N/A 3.424±0.00 N/A 0.554±0.00 1.786±0.19 1.199±0.20 1.000±0.07 1.164±0.00 4.185±1.66 1.417±0.72 9.035±2.45
ENST00000458012 N/A N/A 2.335±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000484574 N/A N/A N/A N/A N/A 3.532±0.00 N/A N/A N/A N/A 1.362±0.00 N/A N/A N/A
ENST00000537335 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.266±0.00
ENST00000541869 0.799±0.00 N/A N/A 0.300±0.00 N/A N/A 0.088±0.00 N/A N/A 0.763±0.00 N/A 1.595±0.60 0.832±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00047U CIL_00047U_0001 CGP 2:112482154-112577150
CIL_00018Y CIL_00018Y_0001 CGP 2:112541915-112589275

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0003899 IEA DNA-directed RNA polymerase activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005730 IDA nucleolus
GO:0005736 IEA DNA-directed RNA polymerase I complex
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006360 TAS transcription from RNA polymerase I promoter
GO:0006361 TAS transcription initiation from RNA polymerase I promoter
GO:0006362 TAS transcription elongation from RNA polymerase I promoter
GO:0006363 TAS termination of RNA polymerase I transcription
GO:0007566 IEA embryo implantation
GO:0009303 IEA rRNA transcription
GO:0010467 TAS gene expression
GO:0017126 IEA nucleologenesis
GO:0032549 IEA ribonucleoside binding
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077469 polr1b polymerase (RNA) I polypeptide B protein_coding Danio_rerio
ENSMUSG00000027395 Polr1b polymerase (RNA) I polypeptide B protein_coding Mus_musculus

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