C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000264221 PAICS-201 ENSG00000128050 9606 + 4:56435749-56461368 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainColonHeartLiverOvaryPlacentaTestisENST00000264221
Transcript ID Adipose Bladder Brain Colon Heart Liver Ovary Placenta Testis
ENST00000264221 1.408±0.00 1.849±0.00 6.054±0.00 4.734±0.00 0.225±0.00 6.449±6.07 6.356±0.94 8.934±3.66 3.159±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001WN CIL_0001WN_0001 CGP 4:56393362-56461368
CIL_0008G9 CIL_0008G9_0001 VISTA 4:56396035-56999166
CIL_0001WO CIL_0001WO_0001 CGP 4:56435741-56503680

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004638 TAS phosphoribosylaminoimidazole carboxylase activity
GO:0004639 IEA:TAS phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005829 TAS cytosol
GO:0006144 TAS purine nucleobase metabolic process
GO:0006189 IEA 'de novo' IMP biosynthetic process
GO:0009113 TAS purine nucleobase biosynthetic process
GO:0009168 TAS purine ribonucleoside monophosphate biosynthetic process
GO:0016020 IDA membrane
GO:0042802 IPI identical protein binding
GO:0044281 TAS small molecule metabolic process
GO:0055086 TAS nucleobase-containing small molecule metabolic process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000117536 Paics-002 protein_coding Mus_musculus 0 1526
ENSMUST00000120912 Paics-001 protein_coding Mus_musculus 0 1526
ENSMUST00000031160 Paics-003 protein_coding Mus_musculus 0 1526
ENSMUST00000153648 Paics-005 nonsense_mediated_decay Mus_musculus 0 651
ENSMUST00000140051 Paics-006 retained_intron Mus_musculus 3e-32 145

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