C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: apolipoprotein L, 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000128284 APOL3 9606 - 22:36140330-36166177 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000349314 APOL3-003 36140330-36160929 protein_coding
  ENST00000361710 APOL3-001 36140330-36166177 protein_coding
  ENST00000397287 APOL3-002 36140330-36166177 protein_coding
  ENST00000397289 APOL3-006 36140330-36160929 nonsense_mediated_decay
  ENST00000397293 APOL3-201 36140330-36160929 protein_coding
  ENST00000422426 APOL3-005 36140330-36160929 nonsense_mediated_decay
  ENST00000424878 APOL3-202 36141027-36149126 protein_coding
  ENST00000426939 APOL3-019 36141716-36160754 nonsense_mediated_decay
  ENST00000432700 APOL3-004 36140330-36160929 nonsense_mediated_decay
  ENST00000472303 APOL3-010 36149075-36160755 nonsense_mediated_decay
  ENST00000485453 APOL3-011 36145544-36156938 processed_transcript
  ENST00000487355 APOL3-009 36141528-36160755 nonsense_mediated_decay
  ENST00000487423 APOL3-012 36141703-36156936 processed_transcript
  ENST00000487783 APOL3-008 36145489-36160755 nonsense_mediated_decay
  ENST00000525184 APOL3-016 36145507-36156885 processed_transcript
  ENST00000528740 APOL3-014 36155720-36156886 processed_transcript
  ENST00000530895 APOL3-015 36146259-36160755 nonsense_mediated_decay
  ENST00000531095 APOL3-007 36154449-36160783 protein_coding
  ENST00000531195 APOL3-018 36145483-36160754 nonsense_mediated_decay
  ENST00000533061 APOL3-013 36159230-36160755 processed_transcript
  ENST00000534251 APOL3-017 36141863-36156949 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000349314ENST00000361710ENST00000397293ENST00000422426ENST00000424878ENST00000426939ENST00000432700
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000349314 39.178±0.00 24.863±0.00 1.280±0.00 17.489±0.00 7.451±6.98 N/A 8.910±0.00 1.051±0.00 N/A 5.994±0.00 3.803±0.86 7.998±0.70 8.404±0.00
ENST00000361710 N/A N/A N/A N/A N/A N/A 0.471±0.00 N/A N/A N/A N/A N/A N/A
ENST00000397293 18.671±0.00 N/A N/A 1.611±0.00 N/A 4.062±3.24 8.328±0.00 0.914±0.00 N/A 0.521±0.00 7.145±2.65 12.861±3.28 0.499±0.00
ENST00000422426 N/A N/A 0.273±0.18 N/A N/A N/A N/A 0.613±0.00 1.578±0.00 1.711±0.00 N/A N/A N/A
ENST00000424878 N/A N/A 1.545±0.00 8.500±0.00 1.859±0.00 1.366±0.00 5.534±0.00 3.500±0.00 6.549±0.00 N/A 1.423±0.00 N/A N/A
ENST00000426939 N/A N/A N/A N/A N/A N/A 3.407±0.00 N/A 8.875±0.00 N/A N/A N/A N/A
ENST00000432700 6.520±0.00 N/A N/A N/A N/A 1.509±0.00 N/A N/A N/A N/A N/A N/A 2.253±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001VM CIL_0001VM_0001 CGP 22:35738736-36166177
CIL_0003GS CIL_0003GS_0002 CGP 22:36140330-36204840

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004871 IMP signal transducer activity
GO:0005319 TAS lipid transporter activity
GO:0005575 ND cellular_component
GO:0005576 IEA extracellular region
GO:0005737 IEA cytoplasm
GO:0006869 IEA lipid transport
GO:0006954 TAS inflammatory response
GO:0007165 IMP signal transduction
GO:0008289 IEA lipid binding
GO:0016020 IDA membrane
GO:0042157 IEA lipoprotein metabolic process
GO:0043123 IMP positive regulation of I-kappaB kinase/NF-kappaB signaling

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000073718 APOL4 apolipoprotein L, 4 protein_coding Danio_rerio
ENSMUSG00000010601 Apol7a apolipoprotein L 7a protein_coding Mus_musculus
ENSMUSG00000044309 Apol7c apolipoprotein L 7c protein_coding Mus_musculus
ENSMUSG00000050014 Apol10b apolipoprotein L 10B protein_coding Mus_musculus
ENSMUSG00000050982 Apol10a apolipoprotein L 10A protein_coding Mus_musculus
ENSMUSG00000056656 Apol8 apolipoprotein L 8 protein_coding Mus_musculus
ENSMUSG00000057346 Apol9a apolipoprotein L 9a protein_coding Mus_musculus
ENSMUSG00000068246 Apol9b apolipoprotein L 9b protein_coding Mus_musculus
ENSMUSG00000068252 Apol7b apolipoprotein L 7b protein_coding Mus_musculus
ENSMUSG00000071716 Apol7e apolipoprotein L 7e protein_coding Mus_musculus
ENSMUSG00000091650 Apol11a apolipoprotein L 11a protein_coding Mus_musculus
ENSMUSG00000091694 Apol11b apolipoprotein L 11b protein_coding Mus_musculus

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