C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: argininosuccinate synthase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000130707 ASS1 9606 + 9:130444929-130501274 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000352480 ASS1-002 130444929-130501274 protein_coding
  ENST00000372386 ASS1-001 130479856-130501178 processed_transcript
  ENST00000372393 ASS1-003 130444988-130501255 protein_coding
  ENST00000372394 ASS1-004 130444962-130501274 protein_coding
  ENST00000422569 ASS1-005 130444992-130471513 protein_coding
  ENST00000443588 ASS1-010 130452223-130471514 protein_coding
  ENST00000467695 ASS1-009 130458518-130479898 retained_intron
  ENST00000470849 ASS1-008 130476549-130489421 retained_intron
  ENST00000492400 ASS1-007 130476284-130489429 processed_transcript
  ENST00000493984 ASS1-006 130466474-130489404 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000352480ENST00000372386ENST00000372393ENST00000372394ENST00000443588ENST00000492400
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000352480 146.567±0.00 18.213±0.00 52.868±0.00 5.170±0.10 56.876±49.22 21.836±13.92 5.316±4.84 145.830±80.78 141.726±134.27 32.977±30.18 12.966±11.13 46.329±16.19 38.117±10.27 35.433±25.54
ENST00000372386 82.776±0.00 14.534±0.00 N/A 17.624±0.00 48.035±0.00 40.843±0.00 N/A 165.350±0.00 186.036±0.00 20.497±0.00 N/A 30.052±10.61 N/A 52.486±0.00
ENST00000372393 N/A 14.381±0.00 N/A 10.633±0.00 38.403±0.00 10.372±0.00 4.883±0.00 80.646±0.00 N/A N/A N/A 23.384±6.40 17.804±2.07 13.816±7.53
ENST00000372394 N/A N/A N/A N/A N/A 0.978±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000443588 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.490±0.00 N/A N/A N/A
ENST00000492400 N/A N/A N/A 5.936±0.00 N/A N/A 0.867±0.00 N/A N/A 2.759±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000936 CIL_000936_0001 VISTA 9:130178260-130779710
CIL_0005UI CIL_0005UI_0001 CGP 9:130265882-130501274
CIL_0008XQ CIL_0008XQ_0001 VISTA 9:130365168-130965841
CIL_0005UH CIL_0005UH_0001 CGP 9:130444929-130638352

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000050 IEA urea cycle
GO:0000052 IMP citrulline metabolic process
GO:0000053 IMP argininosuccinate metabolic process
GO:0001101 IEA response to acid
GO:0001822 IEA kidney development
GO:0001889 IEA liver development
GO:0004055 IMP:IEA argininosuccinate synthase activity
GO:0004066 IEA asparagine synthase (glutamine-hydrolyzing) activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 TAS cytoplasm
GO:0005741 IEA mitochondrial outer membrane
GO:0005764 IEA lysosome
GO:0005783 IEA endoplasmic reticulum
GO:0005829 TAS cytosol
GO:0006526 IEA arginine biosynthetic process
GO:0006529 IEA asparagine biosynthetic process
GO:0006531 IMP aspartate metabolic process
GO:0006953 IEA acute-phase response
GO:0007494 IEA midgut development
GO:0007568 IEA aging
GO:0007584 IEA response to nutrient
GO:0010043 IEA response to zinc ion
GO:0010046 IEA response to mycotoxin
GO:0014075 IEA response to amine
GO:0015643 IEA toxic substance binding
GO:0016597 IMP amino acid binding
GO:0032355 IEA response to estradiol
GO:0032496 IEA response to lipopolysaccharide
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0042493 IEA response to drug
GO:0043005 IEA neuron projection
GO:0043025 IEA neuronal cell body
GO:0043200 IEA response to amino acid
GO:0043204 IEA perikaryon
GO:0043434 IEA response to peptide hormone
GO:0044281 TAS small molecule metabolic process
GO:0044822 IDA poly(A) RNA binding
GO:0045429 IMP positive regulation of nitric oxide biosynthetic process
GO:0048545 IEA response to steroid hormone
GO:0051384 IEA response to glucocorticoid
GO:0060416 IEA response to growth hormone
GO:0060539 IEA diaphragm development
GO:0070062 IDA extracellular vesicular exosome
GO:0070542 IEA response to fatty acid
GO:0070852 IEA cell body fiber
GO:0071222 IEA cellular response to lipopolysaccharide
GO:0071230 IEA cellular response to amino acid stimulus
GO:0071242 IEA cellular response to ammonium ion
GO:0071320 IEA cellular response to cAMP
GO:0071346 IEA cellular response to interferon-gamma
GO:0071356 IEA cellular response to tumor necrosis factor
GO:0071377 IEA cellular response to glucagon stimulus
GO:0071400 IEA cellular response to oleic acid
GO:0071418 IEA cellular response to amine stimulus
GO:0071499 IMP cellular response to laminar fluid shear stress
GO:0071549 IEA cellular response to dexamethasone stimulus
GO:1903038 IMP negative regulation of leukocyte cell-cell adhesion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000032564 ass1 argininosuccinate synthetase 1 protein_coding Danio_rerio
ENSMUSG00000046687 Gm5424 predicted gene 5424 protein_coding Mus_musculus
ENSMUSG00000076441 Ass1 argininosuccinate synthetase 1 protein_coding Mus_musculus

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