C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000397238 AGAP3-001 ENSG00000133612 9606 + 7:151086742-151144432 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastColonHeartKidneyLiverLungMusclePlacentaTestisENST00000397238
Transcript ID Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Placenta Testis
ENST00000397238 3.112±0.00 2.173±0.00 5.303±0.00 10.547±0.00 1.811±1.57 3.718±1.90 1.377±0.00 11.278±8.79 3.478±0.00 6.760±0.00 4.584±2.08

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008T1 CIL_0008T1_0001 VISTA 7:150668461-151272977
CIL_0003TG CIL_0003TG_0001 CGP 7:151081080-151144436
CIL_0004EO CIL_0004EO_0001 CGP 7:151085831-151174745

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000060 IEA protein import into nucleus, translocation
GO:0003924 IEA GTPase activity
GO:0005515 IEA protein binding
GO:0005525 IEA GTP binding
GO:0005622 IEA intracellular
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0006184 IEA GTP catabolic process
GO:0007165 IEA signal transduction
GO:0007264 IEA small GTPase mediated signal transduction
GO:0008060 IEA ARF GTPase activator activity
GO:0008270 IEA zinc ion binding
GO:0015031 IEA protein transport
GO:0016020 IEA membrane
GO:0031593 IEA polyubiquitin binding
GO:0032312 IEA regulation of ARF GTPase activity
GO:0034614 IEA cellular response to reactive oxygen species
GO:0043161 IEA proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043547 IEA positive regulation of GTPase activity
GO:0071944 IEA cell periphery

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000024123 Agap3-201 protein_coding Mus_musculus 0 3493
ENSDART00000128690 protein_coding Danio_rerio 0 804
ENSMUST00000190096 Agap1-002 protein_coding Mus_musculus 0 776
ENSMUST00000027521 Agap1-001 protein_coding Mus_musculus 0 776
ENSMUST00000185417 Agap1-004 retained_intron Mus_musculus 4e-36 158
ENSDART00000125104 agap2-202 protein_coding Danio_rerio 0.00006 55
ENSDART00000086813 agap2-201 protein_coding Danio_rerio 0.00006 55

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