C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transmembrane BAX inhibitor motif containing 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000135926 TMBIM1 9606 - 2:218274192-218292586 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000258412 TMBIM1-001 218274192-218292577 protein_coding
  ENST00000396809 TMBIM1-201 218274201-218285934 protein_coding
  ENST00000413976 TMBIM1-013 218282004-218292513 protein_coding
  ENST00000418569 TMBIM1-016 218278536-218287303 protein_coding
  ENST00000420341 TMBIM1-010 218282118-218292534 protein_coding
  ENST00000425694 TMBIM1-020 218277946-218282208 protein_coding
  ENST00000429501 TMBIM1-015 218277935-218290089 protein_coding
  ENST00000434015 TMBIM1-012 218281940-218292529 protein_coding
  ENST00000437694 TMBIM1-004 218275432-218292503 nonsense_mediated_decay
  ENST00000439306 TMBIM1-023 218277363-218282181 nonsense_mediated_decay
  ENST00000440422 TMBIM1-007 218279335-218292586 protein_coding
  ENST00000444000 TMBIM1-017 218280059-218287291 protein_coding
  ENST00000444183 TMBIM1-009 218279338-218292534 protein_coding
  ENST00000444881 TMBIM1-003 218274201-218286849 protein_coding
  ENST00000445635 TMBIM1-002 218275006-218292513 protein_coding
  ENST00000451181 TMBIM1-019 218280110-218289994 protein_coding
  ENST00000453281 TMBIM1-011 218280077-218292535 protein_coding
  ENST00000453776 TMBIM1-018 218280054-218286008 protein_coding
  ENST00000465082 TMBIM1-006 218274201-218280992 retained_intron
  ENST00000466012 TMBIM1-008 218277935-218292535 retained_intron
  ENST00000476429 TMBIM1-021 218278409-218279539 retained_intron
  ENST00000492966 TMBIM1-022 218277801-218280081 retained_intron
  ENST00000495113 TMBIM1-014 218278479-218292512 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000258412ENST00000396809ENST00000437694ENST00000445635
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000258412 123.877±0.00 13.442±0.00 3.872±0.00 7.121±0.00 26.451±19.94 19.039±9.46 11.362±5.88 15.227±9.54 41.857±27.26 22.992±16.14 20.049±7.70 40.234±26.94 108.612±17.00 14.185±2.47
ENST00000396809 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.890±0.00
ENST00000437694 N/A N/A 5.740±0.00 5.943±0.00 N/A N/A N/A N/A N/A N/A 16.630±0.00 10.727±0.00 N/A N/A
ENST00000445635 N/A N/A 7.171±0.00 N/A 13.606±0.00 20.409±0.00 10.323±0.00 N/A 15.019±0.00 14.729±0.00 N/A 10.953±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005VJ CIL_0005VJ_0001 CGP 2:218264123-218346793
CIL_0005VI CIL_0005VI_0001 CGP 2:218270392-218346793
CIL_0005VH CIL_0005VH_0001 CGP 2:218274192-218368099

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005123 IDA death receptor binding
GO:0005765 IDA lysosomal membrane
GO:0005794 IDA Golgi apparatus
GO:0010008 IDA endosome membrane
GO:0016021 IEA integral component of membrane
GO:0048553 ISS negative regulation of metalloenzyme activity
GO:0070062 IDA extracellular vesicular exosome
GO:0090005 IMP negative regulation of establishment of protein localization to plasma membrane
GO:1902042 IMP negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1902045 IMP negative regulation of Fas signaling pathway
GO:2000504 ISS positive regulation of blood vessel remodeling

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000058323 tmbim1 transmembrane BAX inhibitor motif containing 1 protein_coding Danio_rerio
ENSDARG00000090534 TMBIM1 (2 of 2) transmembrane BAX inhibitor motif containing 1 protein_coding Danio_rerio
ENSMUSG00000006301 Tmbim1 transmembrane BAX inhibitor motif containing 1 protein_coding Mus_musculus

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