C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: transmembrane BAX inhibitor motif containing 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000258412 TMBIM1-001 ENSG00000135926 9606 - 2:218274192-218292577 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000258412
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000258412 123.877±0.00 13.442±0.00 3.872±0.00 7.121±0.00 26.451±19.94 19.039±9.46 11.362±5.88 15.227±9.54 41.857±27.26 22.992±16.14 20.049±7.70 40.234±26.94 108.612±17.00 14.185±2.47

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005VJ CIL_0005VJ_0001 CGP 2:218264123-218346793
CIL_0005VI CIL_0005VI_0001 CGP 2:218270392-218346793
CIL_0005VH CIL_0005VH_0001 CGP 2:218274192-218368099

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005123 IDA death receptor binding
GO:0005765 IDA lysosomal membrane
GO:0005794 IDA Golgi apparatus
GO:0010008 IDA endosome membrane
GO:0016021 IEA integral component of membrane
GO:0048553 ISS negative regulation of metalloenzyme activity
GO:0070062 IDA extracellular vesicular exosome
GO:0090005 IMP negative regulation of establishment of protein localization to plasma membrane
GO:1902042 IMP negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1902045 IMP negative regulation of Fas signaling pathway
GO:2000504 ISS positive regulation of blood vessel remodeling

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000016309 Tmbim1-001 protein_coding Mus_musculus 0 1064
ENSMUST00000113796 Tmbim1-002 protein_coding Mus_musculus 0 1050
ENSMUST00000135384 Tmbim1-003 retained_intron Mus_musculus 0 579
ENSMUST00000152603 Tmbim1-004 retained_intron Mus_musculus 0 529
ENSMUST00000128505 Tmbim1-008 protein_coding Mus_musculus 0 252

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