C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000136738 STAM 9606 + 10:17644125-17715914 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000377500 STAM-003 17644208-17700221 protein_coding
  ENST00000377524 STAM-001 17644125-17715914 protein_coding
  ENST00000445846 STAM-002 17644208-17693281 nonsense_mediated_decay
  ENST00000486183 STAM-004 17684785-17688157 retained_intron
  ENST00000494250 STAM-005 17694926-17700241 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000377524ENST00000494250
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000377524 3.875±0.00 1.526±0.00 5.799±0.82 3.070±0.08 2.466±0.04 3.663±2.72 3.753±1.34 2.298±1.73 2.075±0.39 6.053±5.07 5.748±2.46 5.262±1.46 5.678±1.06
ENST00000494250 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 6.546±0.00 12.318±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006BI CIL_0006BI_0001 CGP 10:17589032-17715914
CIL_00046E CIL_00046E_0002 CGP 10:17644125-17800868

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005070 TAS SH3/SH2 adaptor activity
GO:0005515 IEA protein binding
GO:0005768 IEA endosome
GO:0005829 TAS cytosol
GO:0006886 IEA intracellular protein transport
GO:0007165 TAS signal transduction
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0009967 TAS positive regulation of signal transduction
GO:0016020 IEA membrane
GO:0016197 TAS endosomal transport
GO:0042059 TAS negative regulation of epidermal growth factor receptor signaling pathway
GO:0061024 TAS membrane organization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000002127 stam signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 protein_coding Danio_rerio
ENSMUSG00000026718 Stam signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 protein_coding Mus_musculus

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