C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: abl-interactor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000136754 ABI1 9606 - 10:26746593-26861087 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000346832 ABI1-201 26746596-26861087 protein_coding
  ENST00000359188 ABI1-007 26746593-26860935 protein_coding
  ENST00000376137 ABI1-202 26746596-26861087 protein_coding
  ENST00000376138 ABI1-001 26746593-26861030 protein_coding
  ENST00000376139 ABI1-009 26746593-26860971 protein_coding
  ENST00000376140 ABI1-006 26748570-26860863 protein_coding
  ENST00000376142 ABI1-005 26746593-26860935 protein_coding
  ENST00000376160 ABI1-004 26746593-26860973 protein_coding
  ENST00000376166 ABI1-003 26746593-26860986 protein_coding
  ENST00000376170 ABI1-002 26746593-26860892 protein_coding
  ENST00000473481 ABI1-008 26776626-26823290 processed_transcript
  ENST00000490841 ABI1-203 26746596-26861087 protein_coding
  ENST00000536334 ABI1-204 26746596-26861087 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000376137ENST00000376138ENST00000376139ENST00000376140ENST00000376142ENST00000376160ENST00000376166ENST00000376170ENST00000490841ENST00000536334
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000376137 N/A N/A N/A 4.103±1.54 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000376138 N/A N/A N/A N/A 2.333±0.00 N/A N/A 2.910±0.00 N/A N/A N/A 1.881±0.00 N/A N/A
ENST00000376139 N/A N/A N/A N/A N/A 2.656±0.00 N/A 1.337±0.00 N/A N/A 0.531±0.00 4.824±1.28 N/A N/A
ENST00000376140 16.871±0.00 9.945±0.00 3.828±0.00 17.209±3.07 9.831±0.66 11.257±0.00 6.566±1.97 5.979±0.46 6.670±3.26 10.305±3.97 4.106±1.90 19.560±13.08 13.281±6.85 11.425±2.15
ENST00000376142 N/A N/A N/A 2.572±0.55 N/A N/A 1.957±0.00 N/A N/A N/A 3.039±0.00 N/A N/A N/A
ENST00000376160 N/A N/A N/A N/A N/A N/A 1.089±0.00 4.508±0.00 N/A N/A 0.684±0.00 3.969±1.50 2.268±0.13 1.521±0.00
ENST00000376166 N/A 2.152±0.00 N/A 3.451±0.00 2.149±0.43 5.322±1.22 1.195±0.00 2.342±0.00 2.944±0.00 7.780±1.90 N/A 6.221±3.80 3.598±0.65 2.516±0.06
ENST00000376170 N/A N/A N/A N/A 1.431±0.00 N/A N/A N/A N/A N/A N/A 2.764±0.00 N/A N/A
ENST00000490841 N/A N/A N/A N/A N/A 2.444±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000536334 N/A N/A N/A 2.741±0.00 2.342±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 4.051±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000R4 CIL_0000R4_0001 CGP 10:26438203-26746798
CIL_0000R7 CIL_0000R7_0001 CGP 10:26697659-26861087

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001756 IEA somitogenesis
GO:0005515 IPI:IEA protein binding
GO:0005622 IDA intracellular
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005783 TAS endoplasmic reticulum
GO:0005829 TAS cytosol
GO:0005856 IEA cytoskeleton
GO:0006928 IDA cellular component movement
GO:0007169 TAS transmembrane receptor protein tyrosine kinase signaling pathway
GO:0008092 TAS cytoskeletal protein binding
GO:0008154 NAS actin polymerization or depolymerization
GO:0008285 TAS negative regulation of cell proliferation
GO:0009987 IEA cellular process
GO:0018108 IDA peptidyl-tyrosine phosphorylation
GO:0030027 IDA lamellipodium
GO:0030054 IEA cell junction
GO:0030175 IDA filopodium
GO:0030296 IEA protein tyrosine kinase activator activity
GO:0031209 IDA SCAR complex
GO:0031252 IEA cell leading edge
GO:0032403 IDA protein complex binding
GO:0035855 IEA megakaryocyte development
GO:0038096 TAS Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0043005 IEA neuron projection
GO:0045087 TAS innate immune response
GO:0045211 IEA postsynaptic membrane
GO:0061098 IEA positive regulation of protein tyrosine kinase activity
GO:0070062 IDA extracellular vesicular exosome
GO:0072673 IEA lamellipodium morphogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010155 abi1a abl-interactor 1a protein_coding Danio_rerio
ENSDARG00000062991 abi1b abl-interactor 1b protein_coding Danio_rerio
ENSMUSG00000058835 Abi1 abl-interactor 1 protein_coding Mus_musculus

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