C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ubiquitin specific peptidase 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000138592 USP8 9606 + 15:50424380-50514419 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000307179 USP8-003 50424382-50499776 protein_coding
  ENST00000396444 USP8-001 50424382-50514419 protein_coding
  ENST00000419830 USP8-007 50493185-50499695 retained_intron
  ENST00000425032 USP8-002 50424387-50499415 protein_coding
  ENST00000558091 USP8-017 50426894-50459070 protein_coding
  ENST00000558892 USP8-018 50424399-50444616 processed_transcript
  ENST00000559242 USP8-013 50439026-50462310 nonsense_mediated_decay
  ENST00000559329 USP8-004 50424405-50481702 non_stop_decay
  ENST00000560297 USP8-008 50424380-50449440 protein_coding
  ENST00000560379 USP8-016 50498497-50499407 retained_intron
  ENST00000560527 USP8-014 50458503-50471735 processed_transcript
  ENST00000560730 USP8-005 50424415-50481705 nonsense_mediated_decay
  ENST00000560885 USP8-010 50424405-50462305 processed_transcript
  ENST00000560954 USP8-009 50424382-50459134 processed_transcript
  ENST00000560982 USP8-011 50424448-50441463 protein_coding
  ENST00000561206 USP8-015 50489494-50490430 retained_intron
  ENST00000561211 USP8-012 50424494-50465173 nonsense_mediated_decay
  ENST00000561330 USP8-006 50439043-50481705 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000307179ENST00000396444ENST00000419830ENST00000425032ENST00000559329ENST00000560527ENST00000561330
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000307179 4.193±0.00 6.045±0.00 1.979±0.00 3.966±0.05 3.928±1.16 4.922±0.02 2.576±1.32 5.330±2.49 3.336±0.11 3.554±0.06 1.373±1.19 6.836±4.31 8.689±6.83 23.684±10.94
ENST00000396444 N/A N/A 0.206±0.00 N/A 0.442±0.13 0.353±0.00 0.341±0.00 N/A 0.285±0.00 N/A 0.033±0.00 0.324±0.07 0.206±0.00 0.794±0.00
ENST00000419830 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.746±0.00 N/A N/A N/A
ENST00000425032 2.409±0.00 N/A 0.732±0.00 3.111±0.00 1.443±0.00 1.541±0.00 1.267±0.70 2.328±0.21 2.027±0.00 1.906±0.66 2.322±0.00 1.894±0.40 1.728±0.00 N/A
ENST00000559329 N/A N/A 2.763±0.00 2.833±0.00 N/A 4.771±0.00 1.357±0.00 4.047±0.00 3.575±0.00 5.696±0.00 N/A 3.882±0.00 N/A N/A
ENST00000560527 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.964±0.00 N/A N/A N/A
ENST00000561330 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.492±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00070V CIL_00070V_0001 CGP 15:50275392-50514419
CIL_0002E8 CIL_0002E8_0001 CGP 15:50424380-50546708

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000281 IMP mitotic cytokinesis
GO:0001669 IEA acrosomal vesicle
GO:0004197 TAS cysteine-type endopeptidase activity
GO:0004843 IDA ubiquitin-specific protease activity
GO:0005515 IPI:IEA protein binding
GO:0005622 IEA intracellular
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0005769 IDA early endosome
GO:0005829 IDA cytosol
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0007032 IMP endosome organization
GO:0007265 IEA Ras protein signal transduction
GO:0008283 TAS cell proliferation
GO:0016579 IMP protein deubiquitination
GO:0017124 IEA SH3 domain binding
GO:0019897 IDA extrinsic component of plasma membrane
GO:0030496 IDA midbody
GO:0036459 IEA ubiquitinyl hydrolase activity
GO:0070536 IDA protein K63-linked deubiquitination
GO:0071108 IDA protein K48-linked deubiquitination

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000063719 usp8 ubiquitin specific peptidase 8 protein_coding Danio_rerio
ENSMUSG00000027363 Usp8 ubiquitin specific peptidase 8 protein_coding Mus_musculus

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