C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: G protein-coupled receptor kinase interacting ArfGAP 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000139436 GIT2 9606 - 12:109929792-109996389 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000320063 GIT2-007 109948062-109996291 protein_coding
  ENST00000354574 GIT2-201 109929802-109996389 protein_coding
  ENST00000355312 GIT2-001 109929792-109996224 protein_coding
  ENST00000361006 GIT2-004 109929804-109996304 protein_coding
  ENST00000457474 GIT2-010 109929804-109996295 protein_coding
  ENST00000546613 GIT2-017 109933096-109939022 processed_transcript
  ENST00000547267 GIT2-014 109983608-109992088 retained_intron
  ENST00000547694 GIT2-016 109952680-109959958 retained_intron
  ENST00000547815 GIT2-006 109947322-109996296 protein_coding
  ENST00000548000 GIT2-018 109933112-109943021 processed_transcript
  ENST00000548643 GIT2-012 109980952-109996368 retained_intron
  ENST00000548655 GIT2-019 109934037-109940501 processed_transcript
  ENST00000549999 GIT2-009 109934040-109954550 retained_intron
  ENST00000550186 GIT2-005 109933057-109996224 protein_coding
  ENST00000550480 GIT2-020 109938535-109939685 retained_intron
  ENST00000551209 GIT2-011 109932978-109996224 protein_coding
  ENST00000551455 GIT2-002 109950694-109996373 retained_intron
  ENST00000551721 GIT2-015 109961651-109983180 retained_intron
  ENST00000552978 GIT2-023 109933038-109938977 retained_intron
  ENST00000553118 GIT2-008 109932615-109996389 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000320063ENST00000354574ENST00000355312ENST00000361006ENST00000457474ENST00000547815ENST00000550186ENST00000551209ENST00000551455ENST00000553118
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000320063 N/A N/A N/A N/A N/A 1.903±0.00 N/A N/A N/A 2.858±0.00 N/A 2.551±0.00 N/A N/A
ENST00000354574 N/A N/A N/A N/A 3.097±0.00 1.176±0.00 2.501±0.00 2.105±0.00 1.105±0.00 N/A N/A 2.843±0.00 1.608±0.00 N/A
ENST00000355312 5.669±0.00 8.025±0.00 2.016±0.00 1.812±0.00 2.493±1.26 2.260±0.00 2.963±1.97 4.211±0.00 1.414±0.10 3.101±1.17 7.318±0.00 5.315±2.16 8.059±0.59 2.290±0.00
ENST00000361006 N/A N/A N/A 0.704±0.00 1.080±0.00 2.041±0.36 N/A N/A N/A N/A N/A N/A N/A 6.191±0.50
ENST00000457474 N/A N/A N/A 1.813±0.10 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000547815 N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.029±0.00 N/A N/A N/A N/A
ENST00000550186 N/A N/A N/A N/A N/A N/A N/A 2.020±0.00 N/A N/A N/A N/A N/A N/A
ENST00000551209 N/A N/A N/A N/A N/A N/A N/A N/A 3.607±0.00 N/A 2.969±0.00 N/A N/A N/A
ENST00000551455 N/A N/A 3.983±0.00 N/A 4.516±0.00 3.342±0.00 2.104±0.00 1.723±0.00 N/A N/A N/A 3.400±0.00 N/A N/A
ENST00000553118 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 11.923±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001JH CIL_0001JH_0002 CGP 12:109850943-109983841
CIL_0001GG CIL_0001GG_0002 CGP 12:109900264-109996389
CIL_0001GH CIL_0001GH_0002 CGP 12:109929792-110039763

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005654 IDA nucleoplasm
GO:0005925 IDA focal adhesion
GO:0008060 IEA ARF GTPase activator activity
GO:0008270 IEA zinc ion binding
GO:0008277 TAS regulation of G-protein coupled receptor protein signaling pathway
GO:0032312 IEA regulation of ARF GTPase activity
GO:0043547 IEA positive regulation of GTPase activity
GO:0048266 IEA behavioral response to pain

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000061915 git2a G protein-coupled receptor kinase interactor 2a protein_coding Danio_rerio
ENSMUSG00000041890 Git2 G protein-coupled receptor kinase-interactor 2 protein_coding Mus_musculus

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