C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: G protein-coupled receptor kinase-interactor 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000041890 Git2 10090 - 5:114727407-114775517 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000043283 Git2-002 114727411-114773492 protein_coding
  ENSMUST00000086564 Git2-005 114729575-114773462 protein_coding
  ENSMUST00000112183 Git2-004 114727411-114773434 protein_coding
  ENSMUST00000112185 Git2-001 114727407-114773495 protein_coding
  ENSMUST00000130925 Git2-012 114733864-114748269 protein_coding
  ENSMUST00000131016 Git2-009 114764351-114775517 protein_coding
  ENSMUST00000131582 Git2-008 114764455-114773495 processed_transcript
  ENSMUST00000131993 Git2-010 114748207-114766523 protein_coding
  ENSMUST00000133096 Git2-003 114765675-114773467 retained_intron
  ENSMUST00000135793 Git2-013 114733216-114734166 processed_transcript
  ENSMUST00000144191 Git2-011 114764542-114767153 processed_transcript
  ENSMUST00000146044 Git2-007 114727411-114743868 protein_coding
  ENSMUST00000153756 Git2-014 114747319-114773495 retained_intron
  ENSMUST00000155908 Git2-006 114729870-114769718 protein_coding
  ENSMUST00000178440 Git2-201 114727408-114773492 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000043283ENSMUST00000086564ENSMUST00000112183ENSMUST00000112185ENSMUST00000130925ENSMUST00000146044ENSMUST00000155908ENSMUST00000178440
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000043283 2.774±0.00 N/A 1.542±0.14 3.082±0.30 7.553±1.67 7.071±1.62 0.965±0.00 3.780±1.36 1.895±0.99 N/A 0.619±0.00 4.732±1.43 3.074±0.05 1.239±0.39
ENSMUST00000086564 9.099±1.37 3.826±0.00 5.852±0.08 6.436±3.04 9.537±2.15 4.355±0.85 4.961±0.62 5.717±0.66 4.275±3.39 13.057±3.52 1.520±0.25 8.992±2.99 27.098±7.31 2.279±0.70
ENSMUST00000112183 N/A N/A N/A 4.047±2.07 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000112185 8.864±3.32 9.080±1.06 5.444±0.09 N/A 4.520±1.20 2.875±0.00 3.216±1.70 1.989±0.44 1.809±0.29 15.335±4.15 2.499±0.27 5.921±2.50 7.359±3.08 0.135±0.00
ENSMUST00000130925 N/A N/A N/A 22.575±0.00 N/A N/A N/A N/A N/A N/A N/A 45.649±0.00 111.855±35.64 10.149±0.00
ENSMUST00000146044 N/A 4.250±1.02 N/A N/A 7.577±2.95 3.136±1.00 1.464±0.00 N/A 1.156±0.08 7.577±0.00 N/A 5.974±1.70 N/A N/A
ENSMUST00000155908 N/A N/A N/A N/A 8.866±0.00 N/A N/A N/A N/A N/A 1.336±0.20 9.494±1.11 24.035±8.48 1.699±0.58
ENSMUST00000178440 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.156±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001GG CIL_0001GG_0003 CGP 5:114707760-114775517
CIL_0001GH CIL_0001GH_0003 CGP 5:114727407-114806200

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005654 IEA nucleoplasm
GO:0005925 IEA focal adhesion
GO:0008060 IEA ARF GTPase activator activity
GO:0008270 IEA zinc ion binding
GO:0016301 IEA kinase activity
GO:0016310 IEA phosphorylation
GO:0032312 IEA regulation of ARF GTPase activity
GO:0043547 IEA positive regulation of GTPase activity
GO:0048266 IMP behavioral response to pain

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000061915 git2a G protein-coupled receptor kinase interactor 2a protein_coding Danio_rerio
ENSG00000139436 GIT2 G protein-coupled receptor kinase interacting ArfGAP 2 protein_coding Homo_sapiens

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