C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ubiquitin specific peptidase 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000140455 USP3 9606 + 15:63504511-63594640 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000268049 USP3-201 63529142-63594640 protein_coding
  ENST00000380324 USP3-001 63504611-63591467 protein_coding
  ENST00000538686 USP3-005 63537138-63591467 nonsense_mediated_decay
  ENST00000540797 USP3-202 63504511-63594640 protein_coding
  ENST00000557884 USP3-011 63504612-63559884 nonsense_mediated_decay
  ENST00000558157 USP3-003 63504635-63591444 nonsense_mediated_decay
  ENST00000558218 USP3-017 63586608-63590925 processed_transcript
  ENST00000558285 USP3-004 63532506-63590955 protein_coding
  ENST00000558925 USP3-013 63553333-63556701 retained_intron
  ENST00000559192 USP3-002 63504734-63594640 nonsense_mediated_decay
  ENST00000559257 USP3-008 63537105-63594633 nonsense_mediated_decay
  ENST00000559276 USP3-010 63527833-63537056 protein_coding
  ENST00000559711 USP3-006 63544625-63591136 protein_coding
  ENST00000559718 USP3-019 63588520-63591053 retained_intron
  ENST00000559771 USP3-009 63515446-63556742 protein_coding
  ENST00000559873 USP3-015 63504674-63588396 nonsense_mediated_decay
  ENST00000560070 USP3-014 63504595-63558187 protein_coding
  ENST00000560202 USP3-007 63588729-63594594 nonsense_mediated_decay
  ENST00000561326 USP3-016 63504656-63574152 processed_transcript
  ENST00000561381 USP3-018 63587970-63591003 retained_intron
  ENST00000561442 USP3-012 63504594-63553733 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000268049ENST00000380324ENST00000538686ENST00000540797ENST00000558157ENST00000558285ENST00000559192ENST00000559711ENST00000559718ENST00000559771ENST00000560202
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000268049 1.819±0.00 2.780±0.00 N/A 1.299±0.00 2.026±0.49 2.034±0.00 0.494±0.00 2.787±0.00 1.671±0.86 N/A N/A 4.895±0.00 1.010±0.00 N/A
ENST00000380324 N/A N/A 1.731±0.00 N/A 2.198±0.00 3.348±0.00 0.963±0.00 1.677±0.00 N/A 3.870±0.95 N/A 3.851±0.00 2.607±1.02 4.163±0.00
ENST00000538686 N/A N/A 1.632±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000540797 N/A 2.564±0.00 N/A N/A N/A 1.541±0.00 0.421±0.00 N/A 0.585±0.00 1.014±0.00 0.312±0.00 3.802±0.00 N/A 1.867±0.00
ENST00000558157 2.678±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.496±0.00 N/A N/A
ENST00000558285 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.299±0.00 N/A N/A
ENST00000559192 N/A N/A N/A N/A N/A N/A N/A 0.733±0.00 N/A 1.535±0.48 N/A 0.959±0.00 1.124±0.00 2.016±0.00
ENST00000559711 3.634±0.00 N/A N/A 1.604±0.00 3.173±0.00 N/A 0.796±0.00 4.931±3.36 4.650±0.00 4.449±0.00 1.591±0.00 N/A 2.095±0.65 N/A
ENST00000559718 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 18.450±0.00 N/A 10.208±0.00
ENST00000559771 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 24.278±0.00 11.796±0.00 14.160±0.00
ENST00000560202 N/A 5.096±0.00 N/A N/A N/A N/A N/A N/A 1.808±0.00 N/A N/A 13.625±0.00 1.726±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000278 IMP mitotic cell cycle
GO:0000790 IDA nuclear chromatin
GO:0001046 IEA core promoter sequence-specific DNA binding
GO:0003682 IEA chromatin binding
GO:0004221 IMP ubiquitin thiolesterase activity
GO:0004843 TAS ubiquitin-specific protease activity
GO:0005634 IEA nucleus
GO:0006281 IMP DNA repair
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0008234 IEA cysteine-type peptidase activity
GO:0008270 IEA zinc ion binding
GO:0016578 IDA histone deubiquitination
GO:0031647 IDA regulation of protein stability
GO:0036459 IEA ubiquitinyl hydrolase activity
GO:0042393 IPI histone binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000045641 usp3 ubiquitin specific peptidase 3 protein_coding Danio_rerio
ENSMUSG00000032376 Usp3 ubiquitin specific peptidase 3 protein_coding Mus_musculus

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