C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ATP-binding cassette, sub-family A (ABC1), member 12
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000144452 ABCA12 9606 - 2:214931542-215138428 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000272895 ABCA12-001 214931542-215138428 protein_coding
  ENST00000389661 ABCA12-002 214932622-215032086 protein_coding
  ENST00000412081 ABCA12-003 215075492-215138404 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000272895ENST00000389661
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000272895 N/A 0.021±0.00 N/A 0.014±0.01 0.062±0.00 0.006±0.00 0.030±0.00 0.019±0.00 N/A N/A 0.035±0.02 0.134±0.04 0.126±0.01
ENST00000389661 0.002±0.00 N/A 0.087±0.00 0.004±0.00 0.037±0.00 0.003±0.00 N/A N/A 0.001±0.00 0.005±0.00 0.062±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000AP CIL_0000AP_0002 CGP 2:214725646-215138428
CIL_0005MH CIL_0005MH_0001 CGP 2:214931542-215349773

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005102 IPI receptor binding
GO:0005319 IDA lipid transporter activity
GO:0005515 IPI protein binding
GO:0005524 NAS:IEA ATP binding
GO:0005737 IDA cytoplasm
GO:0005743 IEA mitochondrial inner membrane
GO:0005829 IEA cytosol
GO:0005886 IDA plasma membrane
GO:0006200 IEA ATP catabolic process
GO:0006869 NAS lipid transport
GO:0010875 IDA positive regulation of cholesterol efflux
GO:0016021 NAS integral component of membrane
GO:0016887 IEA ATPase activity
GO:0019725 NAS cellular homeostasis
GO:0030216 IEA keratinocyte differentiation
GO:0031424 IEA keratinization
GO:0032940 IMP secretion by cell
GO:0033700 IMP phospholipid efflux
GO:0034040 IC lipid-transporting ATPase activity
GO:0034191 IPI apolipoprotein A-I receptor binding
GO:0035627 IEA ceramide transport
GO:0043129 IEA surfactant homeostasis
GO:0045055 IMP regulated secretory pathway
GO:0048286 IEA lung alveolus development
GO:0055088 IEA lipid homeostasis
GO:0061436 IEA establishment of skin barrier
GO:0072659 IDA protein localization to plasma membrane
GO:0097209 IDA epidermal lamellar body
GO:2000010 IEA positive regulation of protein localization to cell surface

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074749 abca12 ATP-binding cassette, sub-family A (ABC1), member 12 protein_coding Danio_rerio
ENSMUSG00000050296 Abca12 ATP-binding cassette, sub-family A (ABC1), member 12 protein_coding Mus_musculus

Loading