C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nuclear receptor subfamily 1, group I, member 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000144852 NR1I2 9606 + 3:119780484-119818485 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000337940 NR1I2-001 119782710-119818485 protein_coding
  ENST00000393716 NR1I2-002 119780484-119818485 protein_coding
  ENST00000466380 NR1I2-003 119780484-119818485 protein_coding
  ENST00000474090 NR1I2-004 119782035-119810552 retained_intron
  ENST00000493757 NR1I2-005 119811076-119818484 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000337940ENST00000393716ENST00000466380ENST00000474090ENST00000493757
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000337940 0.006±0.00 0.064±0.00 N/A N/A 0.623±0.00 N/A 0.008±0.00 1.059±1.00 7.751±0.00 0.019±0.00 0.030±0.00 N/A N/A
ENST00000393716 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.069±0.00
ENST00000466380 N/A N/A 0.059±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000474090 N/A N/A N/A N/A 2.344±0.00 3.775±0.00 N/A N/A 0.181±0.00 N/A 4.551±0.00 N/A N/A
ENST00000493757 0.007±0.00 0.007±0.00 N/A 0.113±0.00 0.054±0.00 N/A 0.048±0.00 3.216±0.00 7.425±0.00 0.088±0.00 0.705±0.55 0.025±0.01 0.052±0.02

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005BS CIL_0005BS_0002 CGP 3:119703022-119818485
CIL_0005BP CIL_0005BP_0002 CGP 3:119780484-120094417

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000977 IDA RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001228 IDA RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003707 IEA steroid hormone receptor activity
GO:0003713 TAS transcription coactivator activity
GO:0004879 IDA ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0004887 IEA thyroid hormone receptor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0006805 IDA xenobiotic metabolic process
GO:0007165 TAS signal transduction
GO:0008144 IDA drug binding
GO:0008202 TAS steroid metabolic process
GO:0008270 IEA zinc ion binding
GO:0010467 TAS gene expression
GO:0010628 IEA positive regulation of gene expression
GO:0030522 IDA intracellular receptor signaling pathway
GO:0042738 IDA exogenous drug catabolic process
GO:0042908 IDA xenobiotic transport
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043565 IEA sequence-specific DNA binding
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046618 IDA drug export

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000029766 nr1i2 nuclear receptor subfamily 1, group I, member 2 protein_coding Danio_rerio
ENSMUSG00000022809 Nr1i2 nuclear receptor subfamily 1, group I, member 2 protein_coding Mus_musculus

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