C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: GTPase activating protein (SH3 domain) binding protein 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000145907 G3BP1 9606 + 5:151771045-151812785 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000356245 G3BP1-002 151771943-151805350 protein_coding
  ENST00000394123 G3BP1-001 151771910-151812785 protein_coding
  ENST00000507878 G3BP1-009 151771954-151794222 protein_coding
  ENST00000517947 G3BP1-010 151771954-151795575 nonsense_mediated_decay
  ENST00000518726 G3BP1-003 151771952-151787386 retained_intron
  ENST00000519832 G3BP1-004 151771952-151791750 retained_intron
  ENST00000520006 G3BP1-012 151772279-151791026 protein_coding
  ENST00000520177 G3BP1-006 151771954-151805349 nonsense_mediated_decay
  ENST00000520578 G3BP1-008 151771084-151791063 protein_coding
  ENST00000522367 G3BP1-011 151771954-151795575 nonsense_mediated_decay
  ENST00000522666 G3BP1-013 151772504-151797369 nonsense_mediated_decay
  ENST00000522761 G3BP1-005 151771924-151804225 nonsense_mediated_decay
  ENST00000523519 G3BP1-007 151771045-151791029 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000356245ENST00000394123ENST00000522761
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000356245 10.936±0.00 13.955±0.00 4.351±0.00 4.960±0.21 11.204±2.18 14.500±4.89 7.750±3.14 16.857±9.79 8.589±0.69 10.193±1.38 17.803±12.52 19.084±6.86 20.880±6.49 30.162±5.32
ENST00000394123 N/A N/A 2.544±0.00 1.382±0.00 3.709±0.00 5.003±0.83 2.636±0.00 4.237±0.59 4.706±2.65 6.702±0.00 3.206±1.32 6.911±1.64 3.670±1.74 5.727±0.10
ENST00000522761 17.712±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 20.066±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007IC CIL_0007IC_0002 CGP 5:151661096-151772532
CIL_0001U9 CIL_0001U9_0001 CGP 5:151771045-151924842

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003676 IEA nucleic acid binding
GO:0003677 IEA DNA binding
GO:0003729 IEA mRNA binding
GO:0004003 TAS ATP-dependent DNA helicase activity
GO:0004004 TAS ATP-dependent RNA helicase activity
GO:0004519 IEA endonuclease activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005622 IEA intracellular
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0005886 IEA plasma membrane
GO:0005925 IDA focal adhesion
GO:0006200 TAS ATP catabolic process
GO:0006810 IEA transport
GO:0007265 TAS Ras protein signal transduction
GO:0010494 IEA cytoplasmic stress granule
GO:0032508 TAS DNA duplex unwinding
GO:0044822 IDA poly(A) RNA binding
GO:0090090 IEA negative regulation of canonical Wnt signaling pathway
GO:0090305 IEA nucleic acid phosphodiester bond hydrolysis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000017741 g3bp1 GTPase activating protein (SH3 domain) binding protein 1 protein_coding Danio_rerio
ENSMUSG00000018583 G3bp1 GTPase activating protein (SH3 domain) binding protein 1 protein_coding Mus_musculus

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