C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: histone deacetylase 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000147099 HDAC8 9606 - X:72329516-72573103 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000373554 HDAC8-005 72567585-72572853 protein_coding
  ENST00000373556 HDAC8-003 72567582-72572813 protein_coding
  ENST00000373559 HDAC8-008 72474535-72572812 protein_coding
  ENST00000373560 HDAC8-007 72474411-72572824 protein_coding
  ENST00000373568 HDAC8-006 72351826-72573053 protein_coding
  ENST00000373571 HDAC8-004 72466698-72572843 protein_coding
  ENST00000373573 HDAC8-001 72329516-72573103 protein_coding
  ENST00000373583 HDAC8-010 72329516-72572837 protein_coding
  ENST00000373589 HDAC8-201 72329517-72573103 protein_coding
  ENST00000412342 HDAC8-013 72464668-72572770 nonsense_mediated_decay
  ENST00000415409 HDAC8-012 72462033-72572776 protein_coding
  ENST00000421523 HDAC8-009 72495194-72572627 protein_coding
  ENST00000436675 HDAC8-017 72462011-72572858 nonsense_mediated_decay
  ENST00000439122 HDAC8-002 72473416-72573048 protein_coding
  ENST00000444609 HDAC8-015 72568755-72573079 nonsense_mediated_decay
  ENST00000470998 HDAC8-011 72330832-72462444 processed_transcript
  ENST00000478743 HDAC8-016 72490934-72572843 processed_transcript
  ENST00000486704 HDAC8-014 72571946-72572816 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000373554ENST00000373556ENST00000373559ENST00000373568ENST00000373571ENST00000373573ENST00000373583ENST00000373589ENST00000412342ENST00000415409ENST00000436675ENST00000439122ENST00000444609
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000373554 N/A N/A N/A N/A N/A N/A N/A N/A 1.970±0.00 N/A N/A N/A N/A N/A
ENST00000373556 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.851±0.00 N/A N/A N/A
ENST00000373559 N/A N/A N/A N/A N/A N/A N/A 5.252±0.00 N/A N/A 1.510±0.00 N/A N/A N/A
ENST00000373568 N/A N/A 1.034±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000373571 N/A N/A 1.120±0.00 N/A N/A N/A 0.406±0.00 1.271±0.00 N/A N/A N/A 1.621±0.00 N/A N/A
ENST00000373573 1.896±0.00 0.938±0.00 N/A 2.499±0.18 0.979±0.00 N/A 3.033±0.00 1.717±0.00 N/A 0.464±0.00 N/A 2.526±1.37 2.228±1.13 0.983±0.56
ENST00000373583 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.598±0.00 N/A N/A N/A
ENST00000373589 N/A N/A N/A N/A N/A 1.316±0.00 N/A 3.099±0.00 N/A N/A N/A 3.673±0.00 N/A 1.345±0.00
ENST00000412342 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.444±0.00 1.446±0.00 N/A N/A N/A
ENST00000415409 N/A N/A N/A N/A 1.328±0.00 N/A N/A N/A N/A N/A N/A N/A 1.991±0.00 N/A
ENST00000436675 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.893±0.00 N/A N/A N/A
ENST00000439122 1.062±0.00 2.149±0.00 N/A 1.559±0.00 0.953±0.24 N/A 0.461±0.09 0.737±0.00 0.595±0.26 0.992±0.48 N/A 1.146±0.26 0.896±0.40 0.721±0.00
ENST00000444609 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.809±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006RM CIL_0006RM_0001 CGP X:72301638-72573103
CIL_0006RW CIL_0006RW_0001 CGP X:72329516-72714319

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000118 TAS histone deacetylase complex
GO:0000122 TAS negative regulation of transcription from RNA polymerase II promoter
GO:0000228 TAS nuclear chromosome
GO:0000278 TAS mitotic cell cycle
GO:0004407 TAS histone deacetylase activity
GO:0005634 TAS nucleus
GO:0005737 TAS cytoplasm
GO:0005829 TAS cytosol
GO:0006333 TAS chromatin assembly or disassembly
GO:0006351 IEA transcription, DNA-templated
GO:0007062 IMP sister chromatid cohesion
GO:0008134 TAS transcription factor binding
GO:0016568 TAS chromatin modification
GO:0016575 IEA histone deacetylation
GO:0032041 IEA NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0046872 IEA metal ion binding
GO:0046969 IEA NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0046970 IEA NAD-dependent histone deacetylase activity (H4-K16 specific)
GO:0070932 IEA histone H3 deacetylation
GO:0070933 IEA histone H4 deacetylation
GO:0071922 IMP regulation of cohesin localization to chromatin
GO:0097372 IEA NAD-dependent histone deacetylase activity (H3-K18 specific)

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000067567 Hdac8 histone deacetylase 8 protein_coding Mus_musculus

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