C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: histone deacetylase 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000067567 Hdac8 10090 - X:102284639-102505359 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000087916 Hdac8-001 102284639-102505359 protein_coding
  ENSMUST00000137785 Hdac8-002 102414345-102505345 processed_transcript
  ENSMUST00000148481 Hdac8-003 102407602-102505146 processed_transcript
  ENSMUST00000154024 Hdac8-005 102498156-102504741 retained_intron
  ENSMUST00000154872 Hdac8-004 102405647-102505081 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000087916ENSMUST00000137785ENSMUST00000148481ENSMUST00000154024ENSMUST00000154872
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000087916 4.431±1.15 2.040±0.62 7.036±1.19 3.951±1.05 3.664±1.13 2.357±0.89 1.422±0.21 4.118±0.55 2.005±0.59 3.210±1.05 1.417±0.17 5.033±1.21 1.820±0.67 0.472±0.00
ENSMUST00000137785 N/A 0.581±0.08 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000148481 N/A 0.307±0.01 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000154024 N/A 0.984±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.639±0.02 N/A N/A
ENSMUST00000154872 N/A 0.966±0.00 N/A N/A N/A N/A N/A N/A 0.398±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006RM CIL_0006RM_0002 CGP X:102247381-102505359
CIL_0006RW CIL_0006RW_0002 CGP X:102284639-102644246

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000118 TAS histone deacetylase complex
GO:0004407 TAS histone deacetylase activity
GO:0005634 TAS nucleus
GO:0005737 TAS cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007062 ISS sister chromatid cohesion
GO:0008134 TAS transcription factor binding
GO:0016568 TAS chromatin modification
GO:0032041 IEA NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0046872 IEA metal ion binding
GO:0046969 IEA NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0046970 IEA NAD-dependent histone deacetylase activity (H4-K16 specific)
GO:0070932 IEA histone H3 deacetylation
GO:0070933 IEA histone H4 deacetylation
GO:0071922 ISS regulation of cohesin localization to chromatin
GO:0097372 IEA NAD-dependent histone deacetylase activity (H3-K18 specific)

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000147099 HDAC8 histone deacetylase 8 protein_coding Homo_sapiens

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