C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ubiquitin specific peptidase 16
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000156256 USP16 9606 + 21:29024629-29054488 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000334352 USP16-003 29024651-29054488 protein_coding
  ENST00000399973 USP16-006 29024656-29034919 protein_coding
  ENST00000399975 USP16-001 29024629-29054488 protein_coding
  ENST00000399976 USP16-002 29024629-29054488 protein_coding
  ENST00000474835 USP16-004 29024651-29054488 retained_intron
  ENST00000485067 USP16-005 29052123-29054488 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000334352ENST00000399973ENST00000399975ENST00000399976ENST00000474835ENST00000485067
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000334352 N/A N/A N/A 2.546±1.01 N/A N/A 4.022±3.34 1.332±0.00 N/A N/A 0.733±0.00 N/A N/A N/A
ENST00000399973 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 17.811±0.00 N/A N/A
ENST00000399975 2.475±0.00 4.790±0.00 0.458±0.00 1.997±1.51 3.925±1.63 4.910±2.23 2.882±0.00 3.728±2.16 1.412±0.20 3.422±0.86 4.717±0.00 3.853±0.34 2.329±0.13 8.459±0.39
ENST00000399976 3.811±0.00 5.861±0.00 0.763±0.00 3.077±0.00 3.818±1.59 1.125±0.19 N/A 1.424±0.88 3.692±0.88 3.836±0.00 0.987±0.00 5.290±2.32 5.164±4.26 5.980±0.00
ENST00000474835 N/A 1.530±0.00 0.810±0.00 N/A 1.446±0.00 N/A 0.309±0.00 0.718±0.00 0.576±0.00 N/A N/A N/A N/A N/A
ENST00000485067 N/A 2.612±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.046±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003CH CIL_0003CH_0001 CGP 21:29004384-29054488
CIL_000313 CIL_000313_0001 CGP 21:29024629-29073797

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003713 IDA transcription coactivator activity
GO:0004197 IMP cysteine-type endopeptidase activity
GO:0004221 IDA ubiquitin thiolesterase activity
GO:0004843 IDA ubiquitin-specific protease activity
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 TAS cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006357 ISS regulation of transcription from RNA polymerase II promoter
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0007049 TAS cell cycle
GO:0007067 IDA mitotic nuclear division
GO:0008270 IEA:IDA zinc ion binding
GO:0016578 IDA histone deubiquitination
GO:0035522 ISS monoubiquitinated histone H2A deubiquitination
GO:0036459 IEA ubiquitinyl hydrolase activity
GO:0042393 IDA histone binding
GO:0043130 IDA ubiquitin binding
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0045901 IMP positive regulation of translational elongation
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0051289 IPI protein homotetramerization
GO:0070537 IMP histone H2A K63-linked deubiquitination

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000060633 usp16 ubiquitin specific protease 16 protein_coding Danio_rerio
ENSMUSG00000025616 Usp16 ubiquitin specific peptidase 16 protein_coding Mus_musculus

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