C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: solute carrier family 6 (neurotransmitter transporter), member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000157103 SLC6A1 9606 + 3:10992724-11039247 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000287766 SLC6A1-001 10992724-11039247 protein_coding
  ENST00000425938 SLC6A1-002 10992728-11017327 protein_coding
  ENST00000460480 SLC6A1-004 11017116-11022437 processed_transcript
  ENST00000462473 SLC6A1-003 10992734-11017876 processed_transcript
  ENST00000495636 SLC6A1-005 11033237-11037278 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonKidneyLiverLungOvaryPlacentaENST00000287766ENST00000460480
Transcript ID Bladder Brain Breast Colon Kidney Liver Lung Ovary Placenta
ENST00000287766 0.093±0.00 9.310±0.00 0.296±0.09 0.012±0.00 11.050±10.69 1.929±1.83 0.132±0.00 0.267±0.00 0.195±0.04
ENST00000460480 N/A N/A N/A N/A N/A N/A 0.616±0.00 1.477±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001LQ CIL_0001LQ_0001 CGP 3:10816200-11039247
CIL_00061I CIL_00061I_0001 CGP 3:10992724-11263557

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005328 IEA neurotransmitter:sodium symporter activity
GO:0005332 IEA gamma-aminobutyric acid:sodium symporter activity
GO:0005515 IEA protein binding
GO:0005886 TAS plasma membrane
GO:0005887 IEA integral component of plasma membrane
GO:0006810 NAS transport
GO:0006836 IEA neurotransmitter transport
GO:0007268 TAS synaptic transmission
GO:0007269 TAS neurotransmitter secretion
GO:0007612 IEA learning
GO:0009636 IEA response to toxic substance
GO:0009744 IEA response to sucrose
GO:0009986 IEA cell surface
GO:0010033 IEA response to organic substance
GO:0010243 IEA response to organonitrogen compound
GO:0010288 IEA response to lead ion
GO:0014054 IEA positive regulation of gamma-aminobutyric acid secretion
GO:0014070 IEA response to organic cyclic compound
GO:0014074 IEA response to purine-containing compound
GO:0016020 TAS membrane
GO:0016021 TAS:IEA integral component of membrane
GO:0030424 IEA axon
GO:0032229 IEA negative regulation of synaptic transmission, GABAergic
GO:0032355 IEA response to estradiol
GO:0042220 IEA response to cocaine
GO:0043005 IEA neuron projection
GO:0051260 IEA protein homooligomerization
GO:0051592 IEA response to calcium ion
GO:0051939 IEA gamma-aminobutyric acid import
GO:0055085 TAS transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000039647 slc6a1b solute carrier family 6 (neurotransmitter transporter, GABA), member 1b protein_coding Danio_rerio
ENSDARG00000045944 slc6a1a solute carrier family 6 (neurotransmitter transporter, GABA), member 1a protein_coding Danio_rerio
ENSMUSG00000030310 Slc6a1 solute carrier family 6 (neurotransmitter transporter, GABA), member 1 protein_coding Mus_musculus

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