C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000157985 AGAP1 9606 + 2:235494089-236131800 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000304032 AGAP1-001 235494107-236131800 protein_coding
  ENST00000336665 AGAP1-002 235494107-236126554 protein_coding
  ENST00000402604 AGAP1-006 235524324-235744811 protein_coding
  ENST00000409457 AGAP1-003 235494089-235853202 protein_coding
  ENST00000409538 AGAP1-004 235669604-236126554 protein_coding
  ENST00000418654 AGAP1-007 235908842-236120246 protein_coding
  ENST00000428334 AGAP1-201 235709178-236131800 protein_coding
  ENST00000448025 AGAP1-010 235883395-236036697 protein_coding
  ENST00000453371 AGAP1-005 236045937-236125482 processed_transcript
  ENST00000466575 AGAP1-008 236040612-236120279 retained_intron
  ENST00000482882 AGAP1-009 236040751-236049831 retained_intron
  ENST00000614409 AGAP1-202 235709177-236131800 protein_coding
  ENST00000619456 AGAP1-203 235709177-235852853 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000304032ENST00000336665ENST00000402604ENST00000409538ENST00000428334ENST00000448025ENST00000453371ENST00000466575ENST00000614409ENST00000619456
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000304032 0.744±0.00 0.825±0.00 0.989±0.00 4.427±0.00 1.595±0.00 N/A 0.872±0.77 1.265±0.00 0.546±0.00 1.380±0.94 1.020±0.90 1.746±0.90 0.927±0.31 2.190±1.18
ENST00000336665 N/A N/A 1.721±0.00 N/A 1.302±0.00 2.565±0.00 0.444±0.00 N/A 1.687±0.00 1.498±0.00 N/A 1.761±0.74 0.776±0.05 N/A
ENST00000402604 N/A N/A N/A N/A N/A N/A N/A N/A N/A 6.465±0.00 N/A N/A N/A N/A
ENST00000409538 N/A N/A N/A N/A 1.177±0.00 1.295±0.00 0.142±0.00 N/A N/A 0.451±0.00 N/A N/A N/A N/A
ENST00000428334 0.912±0.00 N/A N/A 2.140±0.00 1.957±0.00 4.942±0.00 N/A 0.821±0.55 N/A N/A 0.225±0.00 0.494±0.00 0.529±0.09 1.623±0.00
ENST00000448025 N/A N/A N/A N/A N/A N/A N/A 1.410±0.00 N/A N/A N/A N/A N/A N/A
ENST00000453371 2.042±0.00 2.152±0.00 N/A N/A N/A N/A N/A 0.678±0.00 1.185±0.00 N/A N/A N/A 1.486±0.09 N/A
ENST00000466575 N/A N/A 35.583±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000614409 1.678±0.00 0.752±0.00 0.751±0.00 10.630±5.57 0.691±0.00 1.008±0.05 1.124±0.98 0.607±0.00 0.605±0.26 N/A 0.885±0.00 1.108±0.14 0.711±0.21 2.390±0.00
ENST00000619456 N/A N/A 7.181±0.00 N/A N/A 10.154±0.00 1.928±0.00 N/A 9.938±0.00 3.183±0.00 1.374±0.00 12.109±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003R3 CIL_0003R3_0001 CGP 2:234951973-236131800
CIL_0003RE CIL_0003RE_0001 CGP 2:235494089-236168369

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005525 IEA GTP binding
GO:0005543 IDA phospholipid binding
GO:0005622 IEA intracellular
GO:0005737 IEA cytoplasm
GO:0006184 IEA GTP catabolic process
GO:0007165 IEA signal transduction
GO:0007264 IEA small GTPase mediated signal transduction
GO:0008060 IEA ARF GTPase activator activity
GO:0008270 IEA zinc ion binding
GO:0015031 IEA protein transport
GO:0016020 IEA membrane
GO:0032312 IEA regulation of ARF GTPase activity
GO:0043547 IEA positive regulation of GTPase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062123 agap1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 protein_coding Danio_rerio
ENSMUSG00000055013 Agap1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 protein_coding Mus_musculus

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