C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: upstream transcription factor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000158773 USF1 9606 - 1:161039251-161045977 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000368019 USF1-003 161039855-161043359 protein_coding
  ENST00000368020 USF1-002 161039251-161044941 protein_coding
  ENST00000368021 USF1-001 161039251-161045977 protein_coding
  ENST00000472217 USF1-005 161039295-161040583 retained_intron
  ENST00000473969 USF1-004 161039920-161045962 nonsense_mediated_decay
  ENST00000491629 USF1-007 161041326-161045908 retained_intron
  ENST00000496363 USF1-006 161040440-161045912 retained_intron
  ENST00000528768 USF1-009 161039940-161041721 protein_coding
  ENST00000529476 USF1-010 161041607-161045939 retained_intron
  ENST00000531842 USF1-011 161040209-161043342 protein_coding
  ENST00000534633 USF1-008 161041390-161045873 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000368019ENST00000368020ENST00000368021ENST00000472217ENST00000473969ENST00000496363ENST00000528768ENST00000529476ENST00000534633
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000368019 N/A 7.588±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000368020 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 8.569±0.00 4.000±1.61 N/A
ENST00000368021 4.790±0.00 N/A 7.390±0.87 5.028±4.16 3.343±0.20 2.668±1.18 5.559±2.95 2.735±1.25 11.326±5.74 4.135±0.00 4.908±4.45 7.636±2.11 4.549±0.52
ENST00000472217 N/A 12.852±0.00 N/A 2.549±0.00 N/A 2.073±0.00 4.437±0.00 1.903±0.00 8.195±0.00 N/A 6.866±0.00 N/A N/A
ENST00000473969 6.245±0.00 7.887±0.00 4.181±0.55 3.244±1.33 2.095±0.00 0.970±0.00 N/A N/A 4.294±0.00 N/A 2.629±0.08 3.950±0.57 N/A
ENST00000496363 N/A N/A N/A N/A N/A N/A N/A 1.765±0.00 N/A N/A 2.951±0.00 N/A N/A
ENST00000528768 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 7.580±0.00 N/A N/A
ENST00000529476 N/A N/A 5.572±0.00 1.952±0.00 7.397±0.00 N/A N/A 4.353±0.00 N/A N/A N/A N/A N/A
ENST00000534633 N/A N/A N/A N/A N/A N/A 2.681±0.00 N/A N/A 1.019±0.00 N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000430 IC regulation of transcription from RNA polymerase II promoter by glucose
GO:0000432 ISS positive regulation of transcription from RNA polymerase II promoter by glucose
GO:0001666 IMP response to hypoxia
GO:0003677 IEA DNA binding
GO:0003690 IEA double-stranded DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003705 IMP RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IDA transcription factor complex
GO:0006006 IEA glucose metabolic process
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 TAS regulation of transcription from RNA polymerase II promoter
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0009411 ISS response to UV
GO:0019086 IDA late viral transcription
GO:0019899 IPI enzyme binding
GO:0019901 IPI protein kinase binding
GO:0032869 IDA cellular response to insulin stimulus
GO:0042593 TAS glucose homeostasis
GO:0042803 TAS protein homodimerization activity
GO:0042826 IPI histone deacetylase binding
GO:0043425 IPI bHLH transcription factor binding
GO:0043565 IDA sequence-specific DNA binding
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0045990 TAS carbon catabolite regulation of transcription
GO:0046982 IPI protein heterodimerization activity
GO:0046983 IEA protein dimerization activity
GO:0051918 IC negative regulation of fibrinolysis
GO:0055088 ISS lipid homeostasis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014463 usf1l upstream transcription factor 1, like protein_coding Danio_rerio
ENSDARG00000041689 usf1 upstream transcription factor 1 protein_coding Danio_rerio
ENSMUSG00000026641 Usf1 upstream transcription factor 1 protein_coding Mus_musculus

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