C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: regulator of calcineurin 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000159200 RCAN1 9606 - 21:34513142-34615142 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000313806 RCAN1-001 34516484-34615142 protein_coding
  ENST00000381132 RCAN1-003 34516484-34526963 protein_coding
  ENST00000381135 RCAN1-201 34516445-34525467 protein_coding
  ENST00000399272 RCAN1-004 34516484-34613843 protein_coding
  ENST00000443408 RCAN1-202 34516445-34614446 protein_coding
  ENST00000463276 RCAN1-009 34523546-34615083 processed_transcript
  ENST00000481448 RCAN1-005 34516484-34526850 protein_coding
  ENST00000482533 RCAN1-006 34516484-34524289 protein_coding
  ENST00000487434 RCAN1-008 34513142-34521583 processed_transcript
  ENST00000487990 RCAN1-010 34516484-34560179 protein_coding
  ENST00000489903 RCAN1-002 34516484-34614446 processed_transcript
  ENST00000492600 RCAN1-007 34521060-34526824 protein_coding
  ENST00000609325 RCAN1-011 34521071-34523117 retained_intron
  ENST00000620920 RCAN1-203 34516445-34524637 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000313806ENST00000381132ENST00000381135ENST00000399272ENST00000443408ENST00000481448ENST00000620920
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000313806 27.168±0.00 12.916±0.00 N/A 19.307±15.02 14.235±11.62 6.112±4.34 24.990±0.00 21.273±0.00 41.679±0.00 11.506±0.00 4.705±3.93 3.791±2.37 10.234±0.36 7.834±1.09
ENST00000381132 6.917±0.00 N/A 11.656±0.00 N/A 7.143±0.00 2.858±0.07 9.048±2.61 8.050±1.66 6.569±0.00 4.877±0.00 N/A 3.183±1.10 22.718±4.99 1.665±0.00
ENST00000381135 N/A N/A N/A N/A N/A N/A N/A N/A N/A 13.172±0.00 N/A 2.179±0.00 N/A N/A
ENST00000399272 N/A N/A N/A 14.048±0.00 N/A N/A N/A 7.089±0.00 N/A N/A 0.731±0.00 2.729±0.08 13.835±4.69 N/A
ENST00000443408 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.564±0.00
ENST00000481448 N/A N/A N/A N/A N/A N/A N/A N/A N/A 10.312±0.00 N/A N/A N/A N/A
ENST00000620920 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.546±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008ON CIL_0008ON_0001 VISTA 21:34142879-34745057
CIL_0007SX CIL_0007SX_0001 VISTA 21:34145397-34749042
CIL_0008OM CIL_0008OM_0001 VISTA 21:34146393-34747421
CIL_0008ZS CIL_0008ZS_0001 VISTA 21:34243666-34847364
CIL_00094R CIL_00094R_0001 VISTA 21:34258399-34859715
CIL_00078G CIL_00078G_0001 CGP 21:34446688-34615142

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002931 IEA response to ischemia
GO:0003677 TAS DNA binding
GO:0003700 TAS sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0006355 TAS regulation of transcription, DNA-templated
GO:0006979 IEA response to oxidative stress
GO:0007165 TAS signal transduction
GO:0007417 TAS central nervous system development
GO:0007519 IEA skeletal muscle tissue development
GO:0007614 IEA short-term memory
GO:0008015 TAS blood circulation
GO:0009612 IEA response to mechanical stimulus
GO:0019722 IEA calcium-mediated signaling
GO:0031987 IEA locomotion involved in locomotory behavior
GO:0033173 IEA calcineurin-NFAT signaling cascade
GO:0042802 IPI identical protein binding
GO:0043627 IEA response to estrogen
GO:0043666 IEA regulation of phosphoprotein phosphatase activity
GO:0048741 IEA skeletal muscle fiber development
GO:0051151 IEA negative regulation of smooth muscle cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003109 rcan1a regulator of calcineurin 1a protein_coding Danio_rerio
ENSDARG00000041157 rcan1b regulator of calcineurin 1b protein_coding Danio_rerio
ENSMUSG00000022951 Rcan1 regulator of calcineurin 1 protein_coding Mus_musculus

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