C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: active BCR-related
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000159842 ABR 9606 - 17:1003518-1229021 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000291107 ABR-003 1005908-1109100 protein_coding
  ENST00000302538 ABR-001 1003518-1179874 protein_coding
  ENST00000536794 ABR-026 1006080-1079146 protein_coding
  ENST00000543210 ABR-005 1006061-1031838 protein_coding
  ENST00000544583 ABR-004 1003527-1187322 protein_coding
  ENST00000570441 ABR-030 1072733-1115436 protein_coding
  ENST00000570525 ABR-031 1091792-1126545 protein_coding
  ENST00000570688 ABR-011 1007269-1010213 retained_intron
  ENST00000571022 ABR-019 1009738-1039597 processed_transcript
  ENST00000571120 ABR-018 1009709-1013194 processed_transcript
  ENST00000571306 ABR-037 1153813-1154619 processed_transcript
  ENST00000571383 ABR-017 1009716-1013146 processed_transcript
  ENST00000571543 ABR-033 1228144-1229021 processed_transcript
  ENST00000571797 ABR-013 1005735-1011920 protein_coding
  ENST00000571945 ABR-025 1067117-1079122 protein_coding
  ENST00000572152 ABR-008 1010785-1050568 nonsense_mediated_decay
  ENST00000572441 ABR-014 1005010-1031802 protein_coding
  ENST00000572585 ABR-006 1003527-1012589 retained_intron
  ENST00000572650 ABR-010 1007238-1010796 retained_intron
  ENST00000573325 ABR-028 1083269-1091776 retained_intron
  ENST00000573559 ABR-012 1006118-1011388 protein_coding
  ENST00000573667 ABR-027 1070038-1083771 retained_intron
  ENST00000573895 ABR-022 1055283-1058047 processed_transcript
  ENST00000574048 ABR-036 1153810-1154952 processed_transcript
  ENST00000574139 ABR-034 1091669-1229004 protein_coding
  ENST00000574257 ABR-009 1012262-1050115 retained_intron
  ENST00000574266 ABR-032 1091799-1179784 protein_coding
  ENST00000574437 ABR-002 1005791-1125755 protein_coding
  ENST00000574544 ABR-024 1050554-1069983 protein_coding
  ENST00000574632 ABR-035 1125324-1154808 processed_transcript
  ENST00000574875 ABR-021 1049980-1050573 retained_intron
  ENST00000575770 ABR-023 1050050-1058047 processed_transcript
  ENST00000575934 ABR-029 1083522-1229004 protein_coding
  ENST00000576668 ABR-016 1012396-1031818 retained_intron
  ENST00000576964 ABR-020 1050094-1083590 processed_transcript
  ENST00000577052 ABR-015 1011576-1031818 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000291107ENST00000302538ENST00000536794ENST00000544583ENST00000572585ENST00000574139ENST00000574257ENST00000575770
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000291107 N/A N/A N/A N/A 2.150±0.00 8.377±0.00 N/A N/A 2.753±0.00 2.184±0.00 N/A N/A N/A
ENST00000302538 6.484±0.00 7.390±0.00 1.501±0.00 33.224±17.26 3.526±0.00 4.803±0.57 12.364±0.00 N/A 1.449±0.35 5.268±0.00 9.894±4.81 3.957±0.62 5.507±0.86
ENST00000536794 N/A N/A 0.961±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000544583 N/A N/A N/A 10.297±0.00 2.281±0.00 N/A N/A 0.930±0.00 0.738±0.00 1.759±0.00 N/A N/A N/A
ENST00000572585 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 12.650±2.30 N/A N/A
ENST00000574139 N/A N/A N/A N/A N/A 30.471±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000574257 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 41.910±0.00 N/A 17.568±0.00
ENST00000575770 N/A N/A N/A N/A N/A 43.746±0.00 N/A N/A N/A 13.100±0.00 20.063±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001Q9 CIL_0001Q9_0001 CGP 17:799313-1003671
CIL_00012J CIL_00012J_0001 CGP 17:997117-1229021
CIL_0001Q6 CIL_0001Q6_0001 CGP 17:1003518-1271460

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005096 TAS GTPase activator activity
GO:0005515 IEA protein binding
GO:0005622 IEA intracellular
GO:0005829 TAS cytosol
GO:0005886 IEA plasma membrane
GO:0007165 IEA signal transduction
GO:0007264 TAS small GTPase mediated signal transduction
GO:0007420 IEA brain development
GO:0016020 IDA membrane
GO:0030036 IEA actin cytoskeleton organization
GO:0030336 IEA negative regulation of cell migration
GO:0030675 IEA Rac GTPase activator activity
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0032496 IEA response to lipopolysaccharide
GO:0032855 IEA positive regulation of Rac GTPase activity
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0035556 IEA intracellular signal transduction
GO:0042472 IEA inner ear morphogenesis
GO:0043065 TAS positive regulation of apoptotic process
GO:0043314 IEA negative regulation of neutrophil degranulation
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0050728 IEA negative regulation of inflammatory response
GO:0050766 IEA positive regulation of phagocytosis
GO:0050885 IEA neuromuscular process controlling balance
GO:0051056 TAS regulation of small GTPase mediated signal transduction
GO:0097190 TAS apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059587 active BCR-related protein_coding Danio_rerio
ENSDARG00000095180 active BCR-related protein_coding Danio_rerio
ENSMUSG00000017631 Abr active BCR-related gene protein_coding Mus_musculus

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