C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: active BCR-related
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000302538 ABR-001 ENSG00000159842 9606 - 17:1003518-1179874 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartLiverLungOvaryPlacentaTestisENST00000302538
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Liver Lung Ovary Placenta Testis
ENST00000302538 6.484±0.00 7.390±0.00 1.501±0.00 33.224±17.26 3.526±0.00 4.803±0.57 12.364±0.00 1.449±0.35 5.268±0.00 9.894±4.81 3.957±0.62 5.507±0.86

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001Q9 CIL_0001Q9_0001 CGP 17:799313-1003671
CIL_00012J CIL_00012J_0001 CGP 17:997117-1229021
CIL_0001Q6 CIL_0001Q6_0001 CGP 17:1003518-1271460

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005096 TAS GTPase activator activity
GO:0005515 IEA protein binding
GO:0005622 IEA intracellular
GO:0005829 TAS cytosol
GO:0005886 IEA plasma membrane
GO:0007165 IEA signal transduction
GO:0007264 TAS small GTPase mediated signal transduction
GO:0007420 IEA brain development
GO:0016020 IDA membrane
GO:0030036 IEA actin cytoskeleton organization
GO:0030336 IEA negative regulation of cell migration
GO:0030675 IEA Rac GTPase activator activity
GO:0032496 IEA response to lipopolysaccharide
GO:0032855 IEA positive regulation of Rac GTPase activity
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0035556 IEA intracellular signal transduction
GO:0042472 IEA inner ear morphogenesis
GO:0043065 TAS positive regulation of apoptotic process
GO:0043314 IEA negative regulation of neutrophil degranulation
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0050728 IEA negative regulation of inflammatory response
GO:0050766 IEA positive regulation of phagocytosis
GO:0050885 IEA neuromuscular process controlling balance
GO:0051056 TAS regulation of small GTPase mediated signal transduction
GO:0097190 TAS apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000072740 Abr-001 protein_coding Mus_musculus 0 3988
ENSMUST00000094012 Abr-002 protein_coding Mus_musculus 0 3869
ENSMUST00000108407 Abr-201 protein_coding Mus_musculus 0 3771
ENSMUST00000108408 Abr-003 protein_coding Mus_musculus 0 3227
ENSMUST00000065028 Abr-006 protein_coding Mus_musculus 0 2996
ENSMUST00000141442 Abr-010 retained_intron Mus_musculus 0 1290
ENSMUST00000164107 Bcr-201 protein_coding Mus_musculus 0 891
ENSMUST00000151526 Abr-004 protein_coding Mus_musculus 0 723
ENSDART00000082965 protein_coding Danio_rerio 0 654
ENSMUST00000130364 Abr-007 nonsense_mediated_decay Mus_musculus 0 632
ENSMUST00000176179 Abr-011 protein_coding Mus_musculus 0 616
ENSMUST00000131059 Abr-009 processed_transcript Mus_musculus 0 568
ENSMUST00000155035 Abr-008 protein_coding Mus_musculus 0 538
ENSMUST00000176024 Abr-012 protein_coding Mus_musculus 0 446
ENSDART00000062073 BCR (1 of 2)-201 protein_coding Danio_rerio 0 228
ENSDART00000137009 BCR (1 of 2)-001 protein_coding Danio_rerio 0 228
ENSMUST00000137261 Abr-005 processed_transcript Mus_musculus 6e-27 128

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